Evidence map›Paper›PMID 36467981›Full record

ArticleJournal of analytical methods in chemistry2022

Establishment of Quality Evaluation Method for Yinqiao Powder: A Herbal Formula against COVID-19 in China.

Huimin Zhang, Lin Xu, Jian Song, Aijun Zhang, Xiao Zhang, Qingjun Li, Xinyan Qu, Ping Wang

Abstract read
In one paragraph

Article in Journal of analytical methods in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. [Comparison of anti-inflammatory, antibacterial and analgesic activities of formulated granulesNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2025
    Article
  4. The Role of Yinqiao Powder in ModulatingInfection and drug resistance · 2025
    Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huimin ZhangShandong Academy of Chinese Medicine, Jinan 250014, China.ORCID https://orcid.org/0000-0002-2850-6236
Lin XuShandong University of Traditional Chinese Medicine, Jinan 250355, China.ORCID https://orcid.org/0000-0003-3984-5951
Jian SongShandong University of Traditional Chinese Medicine, Jinan 250355, China.ORCID https://orcid.org/0000-0003-3704-6152
Aijun ZhangTraditional Chinese Medicine Research Institute, Shandong Hongjitang Pharmaceutical Group Co Ltd., Jinan 250103, China.ORCID https://orcid.org/0000-0003-2656-9003
Xiao ZhangShandong University of Traditional Chinese Medicine, Jinan 250355, China.ORCID https://orcid.org/0000-0003-2345-741X
Qingjun LiShandong University of Traditional Chinese Medicine, Jinan 250355, China.ORCID https://orcid.org/0000-0001-5538-7511
Xinyan QuLaboratory of Immunology for Environment and Health, Shandong Analysis and Test Center, Qilu University of Technology (Shandong Academy of Sciences), Jinan 250014, China.ORCID https://orcid.org/0000-0001-6800-978X
Ping WangShandong Academy of Chinese Medicine, Jinan 250014, China.ORCID https://orcid.org/0000-0001-7517-8688

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yinqiao powder, with significant anti-inflammatory and antiviral effects, is a classical formula for the treatment of febrile diseases in China. During the SARS period in 2003, Yinqiao powder showed a good antipyretic effect. It also plays a major role in the treatment for COVID-19 in China. Although there are many studies on the chemical compositions and pharmacological effects of Yinqiao powder, there are few studies on the quality standard system of it. In our study, a systematic quality evaluation method of Yinqiao powder combining HPLC fingerprint with quantitative analysis of multi-components by single marker (QAMS) based on network pharmacology and UPLC-Q-Exactive-Orbitrap-MS was established for the first time. In the UPLC-Q-Exactive-Orbitrap-MS experiment, a total of 53 compounds were identified in the extract solution of Yinqiao powder. In addition, 33 blood components were characterized, 23 of which were prototypes. The results of network pharmacology analysis showed that Yinqiao powder may inhibit inflammatory responses by suppressing IL-6, CXCL2, TNF

Identifiers

PMID36467981
PMCPMC9718632

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.