Evidence map›Paper›PMID 36467896›Full record

ArticleRheumatology and immunology research2021

Tocilizumab for Severe COVID-19 Pneumonia: Experience from 5 Geriatric Chinese Patients with 6 Months Follow-up.

Aihua Liu, Zhe Chen, Yongjing Cheng, Xutao Wang, Ming Gao, Cibo Huang

Abstract read
In one paragraph

Article in Rheumatology and immunology research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aihua LiuDepartment of Rheumatology and Immunology, Beijing Hospital, National Centre of Gerontology, Beijing, China.
Zhe ChenDepartment of Rheumatology and Immunology, Beijing Hospital, National Centre of Gerontology, Beijing, China.
Yongjing ChengDepartment of Rheumatology and Immunology, Beijing Hospital, National Centre of Gerontology, Beijing, China.ORCID https://orcid.org/0000-0002-5453-7298
Xutao WangDepartment of Emergency, Beijing Hospital, National Centre of Gerontology, Beijing, China.
Ming GaoDepartment of Rheumatology and Immunology, Beijing Hospital, National Centre of Gerontology, Beijing, China.
Cibo HuangDepartment of Rheumatology and Immunology, Beijing Hospital, National Centre of Gerontology, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To enable physicians to understand the efficacy and safety of Tocilizumab (TCZ) in patients with severe coronavirus disease-2019 (COVID-19). Methods: We respectively reviewed the clinical records, laboratory results, and chest computed tomography (CT) scans of 5 geriatric patients with severe COVID-19 treated with TCZ during their inpatient hospitalization period in Wuhan from February 08, 2020 to April 04, 2020. The survival status of the patients in the third and the sixth month after being discharged was followed up and recorded. Results: On the fourteenth day after TCZ administration, periphery oxygen saturation rate (SpO Conclusion: TCZ may be an efficient therapeutic option for patients with COVID-19. However, the possibility of VSPs delay, secondary infection, serum protective antibody tilter attenuation, and long-term survival status should be addressed before TCZ therapy initiation.

Indexed as

coronavirus disease 2019follow-upinterleukin-6Tocilizumabvirus shedding periods

Identifiers

PMID36467896
PMCPMC9524772

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.