Evidence map›Paper›PMID 36467836›Full record

ArticleEJHaem2022

Lymphoplasmacytic lymphoma and marginal zone lymphoma involving bone marrow: A diagnostic dilemma. Useful clinicopathological features to accurate the diagnosis.

Patricia García-Abellás, Ana Ferrer Gómez, Diego Bueno Sacristán, Miguel Piris Villaespesa, María Talavera Yagüe, María Eugenia Reguero Callejas, Mónica García-Cosío

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. MYD88 mutation-positive indolent B-cell lymphoma with CNS involvement: Bing-Neel syndrome mimickers.Journal of clinical and experimental hematopathology : JCEH · 2024
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Patricia García-AbellásDepartment of Pathology Ramón y Cajal Universitary Hospital Madrid Spain.
Ana Ferrer GómezDepartment of Pathology Ramón y Cajal Universitary Hospital Madrid Spain.
Diego Bueno SacristánDepartment of Pathology Ramón y Cajal Universitary Hospital Madrid Spain.
Miguel Piris VillaespesaDepartment of Hematology Ramón y Cajal Universitary Hospital Madrid Spain.
María Talavera YagüeDepartment of Genetics Ramón y Cajal Universitary Hospital Madrid Spain.
María Eugenia Reguero CallejasDepartment of Pathology Ramón y Cajal Universitary Hospital Madrid Spain.
Mónica García-CosíoHead of Hematopathology Department Ramón y Cajal Universitary Hospital; Alcalá University, Madrid, Spain; Instituto Ramon y Cajal de Investigacion Sanitaria, Madrid, Spain; CIBERONC Madrid Spain.
Hospital Universitario Ramón y Cajal · ESCentro de Investigación Biomédica en Red de Cáncer · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphoplasmacytic lymphoma (LPL) and marginal zone lymphoma (MZL) frequently infiltrate the bone marrow with similar histologic and immunohistochemical characteristics posing diagnostic problems. Bone marrow biopsy specimens from 25 LPL and 16 MZL have been studied, correlating with clinical, laboratory parameters and the MYD88_p.L265P mutation. Paratrabecular and interstitial infiltration pattern, serum IgM paraprotein levels, and MYD88_p.L265P mutation were significantly more frequent in LPL. Nodular or intrasinusoidal pattern with lymphocytosis and splenomegaly were associated with MZL diagnosis. Different clinical and histological parameters should be collected when LPL or MZL is suspected in bone marrow biopsy specimens.

Indexed as

bone marrowdiagnosislymphoplasmacytic lymphomamarginal zone lymphomaWaldenström macroglobulinemia

Identifiers

PMID36467836
PMCPMC9713066
OpenAlexW4302013311

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.