Evidence map›Paper›PMID 36467814›Full record

ArticleEJHaem2022

Ibrutinib and rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone in patients with previously untreated non-germinal centre B-cell-like diffuse large B-cell lymphoma: A Chinese subgroup analysis of the phase III PHOENIX trial.

Jun Zhu, Xiaonan Hong, Yu Qin Song, Brendan Hodkinson, Sriram Balasubramanian, Songbai Wang, Qingyuan Zhang, Yuankai Shi, Huiqiang Huang, Huilai Zhang and 8 more

Open access · diamondAbstract read
In one paragraph

Article in EJHaem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Synergistic effect of venetoclax and ibrutinib on ibrutinib-resistant ABC-type DLBCL cells.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2024
    Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 10 institutions in 4 countries.

Jun ZhuBeijing University Cancer Hospital and Institute Beijing China.
Xiaonan HongFudan University Cancer Hospital Shanghai China.
Yu Qin SongBeijing University Cancer Hospital and Institute Beijing China.
Brendan HodkinsonOncology Translational Research Janssen Research and Development Spring House Pennsylvania USA.
Sriram BalasubramanianOncology Translational Research Janssen Research and Development San Diego California USA.
Songbai WangOncology Translational Research Janssen Research and Development Raritan New Jersey USA.
Qingyuan ZhangAffiliated Cancer Hospital of Harbin Medical University Harbin China.
Yuankai ShiNational Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs Beijing China.ORCID https://orcid.org/0000-0002-3342-4964
Huiqiang HuangSun Yat-sen University Cancer Center Guangzhou China.
Huilai ZhangTianjin Cancer Hospital Heping China.
Yan ZhuJanssen Research and Development Raritan New Jersey USA.
Stephen Martin ShreeveClinical Oncology Janssen Research and Development San Diego California USA.
Steven SunClinical Biostats Janssen Research and Development Raritan New Jersey USA.
Ze WangXian Janssen Pharmaceuticals Medical Affairs Beijing China.
Xiaocan WangXian Janssen Pharmaceuticals Medical Affairs Beijing China.
Yue FanOncology Translational Research Janssen Research and Development Shanghai China.
Wyndham WilsonNational Cancer Institute National Institutes of Health Bethesda Maryland USA.
Jessica VermeulenClinical Oncology Janssen Research and Development Leiden The Netherlands.
Janssen (United States) · USJanssen (Belgium) · BEPeking University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNFudan University Shanghai Cancer Center · CNHarbin Medical University · CNJanssen (Netherlands) · NLNational Institutes of Health · USSun Yat-sen University · CNTianjin Medical University Cancer Institute and Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this post hoc subgroup analysis of 200 patients enrolled in China from the phase III PHOENIX trial (

Indexed as

ChinaDLBCLibrutinibpreviously untreated

Identifiers

PMID36467814
PMCPMC9713042
OpenAlexW4293601881

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.