Evidence map›Paper›PMID 36467813›Full record

ArticleEJHaem2022

Skin cancer in essential thrombocythaemia and polycythaemia vera patients treated with hydroxycarbamide.

Abhinav Mathur, Joakim Edman, Livia Liang, Neil W Scott, Henry G Watson

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJHaem, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Abhinav MathurDepartment Haematology Aberdeen Royal Infirmary Foresterhill Health Campus Aberdeen UK.ORCID https://orcid.org/0000-0002-6952-5927
Joakim EdmanSchool of Medicine Medical Sciences and Nutrition Aberdeen University Aberdeen UK.
Livia LiangNational University Health System National University Hospital Singapore Singapore.
Neil W ScottInstitute of Applied Health Sciences University of Aberdeen, Polwarth Building, Foresterhill Aberdeen UK.
Henry G WatsonDepartment Haematology Aberdeen Royal Infirmary Foresterhill Health Campus Aberdeen UK.
University of Aberdeen · GBAberdeen Royal Infirmary · GBNational University Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxycarbamide (HC) is used as a cytoreductive treatment in myeloproliferative neoplasms (MPN). Observational studies have raised the possibility that HC contributes to the development of secondary malignancies, including skin tumours in MPN patients. In this retrospective observational study, we report a single-centre experience of 324 HC-treated MPN patients with long-term follow-up, compared to 47 MPN patients not on HC. Thirty-three patients (10.2%) (HC) versus one patient (2.1%) (no HC) developed skin tumours during follow-up (Hazard ratios [HR] 5.70, 95% confidence intervals 0.66-48.09,

Indexed as

essential thrombocythaemiahydroxycarbamidemelanomamyeloproliferative neoplasmnon‐melanoma skin cancerpolycythaemia vera

Identifiers

PMID36467813
PMCPMC9713223
OpenAlexW4295851900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.