ArticleJournal of oncology2022
The Prognostic Significance of HALP Index for Colon Cancer Patients in a Hispanic-Based Population.
Article in Journal of oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Prognostic significance of hemoglobin, albumin, lymphocyte and platelet score in solid tumors: a pooled study.Frontiers in immunology · 2024Pooled it
- Beyond Simple Ratios: Can the Preoperative HALP Score Provide a More Effective Inflammatory Biomarker for Colon Cancer Survival?Medicina (Kaunas, Lithuania) · 2026Article
- The role of the HALP score and inflammatory biomarkers in differentiating complicated and uncomplicated acute appendicitis: a retrospective cohort study.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Prognostic value of the HALP index, erythrocyte sedimentation rate, and rheumatoid factor in rheumatoid arthritis: A laboratory-based multivariate analysis.Journal of medical biochemistry · 2026Article
- Prognostic Value of HALP and PNI Scores in Predicting 6-Month Mortality Among Geriatric Hip Fracture Patients.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- A novel nomogram based on HALP score for predicting time to glycemic stability in hospitalized type 2 diabetes patients.Frontiers in endocrinology · 2026Article
- The role of the preoperative HALP score in predicting pathological T and N categories in colon cancer: a single-center retrospective study.Frontiers in oncology · 2026Article
- Could the HALP score indicate poor prognosis in colorectal cancer patients?Turkish journal of surgery · 2025Article
- Article
- Article
- The Prognostic Significance of HALP Index for Colon Cancer Patients in a Hispanic-Based Population.Journal of oncology · 2022Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Survival and recurrence rates following locoregional colon cancer surgical resection are highly variable. Currently used tools to assess patient risk are still imperfect. In the present work, we evaluate, for the first time, the prognostic value of the recently developed HALP (hemoglobin, albumin, lymphocyte, and platelet) index in Hispanic colon cancer patients. Results: We included 640 patients (49.8% female). The optimal HALP cut-off value was 15.0. A low HALP index was statistically significantly associated with a higher TNM stage. Low HALP score was statistically significantly associated with shorter median OS in the Kaplan-Meier analysis (73.5 vs. 84.8 months) and in the multivariate Cox regression analysis (HR = 1.942, 95% CI = 1.647-2.875). There was no significant association between the HALP score and DFS. Conclusions: Our findings show that the HALP index is an independent factor associated with survival in Hispanic patients, despite recurrence. It seems to reflect both the anatomical extent of the disease and traditionally unaccounted nutritional and inflammatory factors that are significant for prognosis.
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