Evidence map›Paper›PMID 36466883›Full record

ArticleFrontiers in immunology2022

Detection and evolutionary dynamics of somatic FAS variants in autoimmune lymphoproliferative syndrome: Diagnostic implications.

Laura Batlle-Masó, Marina Garcia-Prat, Alba Parra-Martínez, Clara Franco-Jarava, Aina Aguiló-Cucurull, Pablo Velasco, María Antolín, Jacques G Rivière, Andrea Martín-Nalda, Pere Soler-Palacín and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Laura Batlle-MasóInfection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Marina Garcia-PratInfection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Alba Parra-MartínezInfection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Clara Franco-JaravaJeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Spain.
Aina Aguiló-CucurullJeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Spain.
Pablo VelascoPediatric Oncology and Hematology Department, Vall d'Hebron University Hospital (HUVH), Barcelona, Spain.
María AntolínDepartment of Clinical and Molecular Genetics, Vall d'Hebron University Hospital (HUVH), Barcelona, Spain.
Jacques G RivièreInfection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Andrea Martín-NaldaInfection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Pere Soler-PalacínInfection in Immunocompromised Pediatric Patients Research Group, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.
Mónica Martínez-GalloJeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Spain.
Roger ColobranJeffrey Modell Diagnostic and Research Center for Primary Immunodeficiencies, Barcelona, Spain.
Vall d'Hebron Hospital Universitari · ESVall d'Hebron Institut de Recerca · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoimmune lymphoproliferative syndrome (ALPS) is a rare primary immune disorder characterized by impaired apoptotic homeostasis. The clinical characteristics include lymphoproliferation, autoimmunity (mainly cytopenia), and an increased risk of lymphoma. A distinctive biological feature is accumulation (>2.5%) of an abnormal cell subset composed of TCRαβ

Indexed as

Autoimmune Lymphoproliferative SyndromeBrain NeoplasmsGliomaChildHumansautoimmune lymphoproliferative syndromeFASgeneticsinborn errors of immunitynext-generation sequencingprimary immunodeficienciessomatic mutation

Identifiers

PMID36466883
PMCPMC9716137
OpenAlexW4309379076

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.