Evidence map›Paper›PMID 36466769›Full record

Review3 Biotech2023

Antibacterial potential of chalcones and its derivatives against

Larissa da Silva, Isydorio Alves Donato, Cicera Alane Coelho Gonçalves, Jackelyne Roberta Scherf, Hélcio Silva Dos Santos, Edna Mori, Henrique Douglas Melo Coutinho, Francisco Assis Bezerra da Cunha

Open access · greenAbstract readReview
In one paragraph

Review in 3 Biotech, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 28 citations in OpenAlex.

  1. Evaluation of Chalcone (ACS omega · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Evaluation of the Activity of Amino Chalcone AgainstPharmaceuticals (Basel, Switzerland) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Synthesis andFrontiers in chemistry · 2024
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Larissa da SilvaLaboratory of Semi-Arid Bioprospecting (LABSEMA), Department of Biological Chemistry, URCA, Crato, CE Brazil.
Isydorio Alves DonatoLaboratory of Semi-Arid Bioprospecting (LABSEMA), Department of Biological Chemistry, URCA, Crato, CE Brazil.
Cicera Alane Coelho GonçalvesLaboratory of Semi-Arid Bioprospecting (LABSEMA), Department of Biological Chemistry, URCA, Crato, CE Brazil.
Jackelyne Roberta ScherfGraduate Program in Pharmaceutical Sciences, Federal University of Pernambuco, UFPE, Recife, PE Brazil.
Hélcio Silva Dos SantosLaboratory of Chemistry of Natural and Synthetic Product, State university of Ceará, UECE, Fortaleza, CE Brazil.
Edna MoriCECAPE, College of Dentistry, Juazeiro do Norte, CE 63024-015 Brazil.
Henrique Douglas Melo CoutinhoLaboratory of Microbiology and Molecular Biology (LMBM), Department of Biological Chemistry, URCA, Crato, CE Brazil.ORCID 0000-0002-6634-4207
Francisco Assis Bezerra da CunhaLaboratory of Semi-Arid Bioprospecting (LABSEMA), Department of Biological Chemistry, URCA, Crato, CE Brazil.
Universidade Regional do Cariri · BRUniversidade Estadual do Ceará · BRUniversidade Federal de Pernambuco · BRUniversidade Federal do Cariri · BR

Funding

Austrian Science Fund FWF P 20001Biotechnology and Biological Sciences Research Council BBS/E/C/00004955
6 · The paper itself

Abstract

Chalcones are natural substances found in the metabolism of several botanical families. Their structure consists of 1,3-diphenyl-2-propen-1-one and they are characterized by having in their chains an α, β-unsaturated carbonyl system, two phenol rings and a three-carbon chain that unites them. In plants, Chalcones are mainly involved in the biosynthesis of flavonoids and isoflavonoids through the phenylalanine derivation. This group of substances has been shown to be a viable alternative for the investigation of its antibacterial potential, considering the numerous biological activities reported and the increase of the microbial resistance that concern global health agencies. Supplementary Information: The online version contains supplementary material available at 10.1007/s13205-022-03398-7.

Indexed as

BioactivityEfflux pumpMulti-resistanceStructure–activity relationship

Identifiers

PMID36466769
PMCPMC9712905
OpenAlexW4310482566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.