Evidence map›Paper›PMID 36466668›Full record

ArticleFrontiers in microbiology2022

The protective immunity induced by intranasally inoculated serotype 63 chimpanzee adenovirus vector expressing human respiratory syncytial virus prefusion fusion glycoprotein in BALB/c mice.

Lei Huang, Mei-Qing Liu, Chang-Qing Wan, Ning-Ning Cheng, Yan-Bin Su, Yan-Peng Zheng, Xiang-Lei Peng, Jie-Mei Yu, Yuan-Hui Fu, Jin-Sheng He

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lei HuangCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Mei-Qing LiuCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Chang-Qing WanCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Ning-Ning ChengCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Yan-Bin SuCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Yan-Peng ZhengCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Xiang-Lei PengCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Jie-Mei YuCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Yuan-Hui FuCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Jin-Sheng HeCollege of Life Sciences and Bioengineering, Beijing Jiaotong University, Beijing, China.
Beijing Jiaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human respiratory syncytial virus (RSV) is a ubiquitous pediatric pathogen causing serious lower respiratory tract disease worldwide. No licensed vaccine is currently available. In this work, the coding gene for mDS-Dav1, the full-length and prefusion conformation RSV fusion glycoprotein (F), was designed by introducing the stabilized prefusion F (preF) mutations from DS-Cav1 into the encoding gene of wild-type RSV (

Indexed as

human respiratory syncytial virusimmune efficacyintranasal immunizationprefusion fusion glycoproteinserotype 63 chimpanzee adenoviral vectorvaccine

Identifiers

PMID36466668
PMCPMC9716990
OpenAlexW4309376691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.