Evidence map›Paper›PMID 36466655›Full record

ReviewFrontiers in microbiology2022

Gut microbiota, pathogenic proteins and neurodegenerative diseases.

Wei Wei, Shixu Wang, Chongchong Xu, Xuemei Zhou, Xinqing Lian, Lin He, Kuan Li

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Wei WeiThe Mental Hospital of Yunnan Province, Mental Health Center Affiliated to Kunming Medical University, Kunming, China.
Shixu WangSchool of Forensic Medicine, Kunming Medical University, Kunming, China.
Chongchong XuSchool of Forensic Medicine, Kunming Medical University, Kunming, China.
Xuemei ZhouSchool of Forensic Medicine, Kunming Medical University, Kunming, China.
Xinqing LianSchool of Forensic Medicine, Kunming Medical University, Kunming, China.
Lin HeThe Mental Hospital of Yunnan Province, Mental Health Center Affiliated to Kunming Medical University, Kunming, China.
Kuan LiSchool of Forensic Medicine, Kunming Medical University, Kunming, China.
Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the world's population ages, neurodegenerative diseases (NDs) have brought a great burden to the world. However, effective treatment measures have not been found to alleviate the occurrence and development of NDs. Abnormal accumulation of pathogenic proteins is an important cause of NDs. Therefore, effective inhibition of the accumulation of pathogenic proteins has become a priority. As the second brain of human, the gut plays an important role in regulate emotion and cognition functions. Recent studies have reported that the disturbance of gut microbiota (GM) is closely related to accumulation of pathogenic proteins in NDs. On the one hand, pathogenic proteins directly produced by GM are transmitted from the gut to the central center

Indexed as

dietary therapyfecal microbiota transplantationgut microbiotainflammatory factorsneurodegenerative diseasespathogenic proteins

Identifiers

PMID36466655
PMCPMC9715766
OpenAlexW4309458085

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.