ArticleFrontiers in microbiology2022
Correlation analysis between gut microbiota characteristics and melasma.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Imaging and Microorganism Analyses of the Effects of OralNutrients · 2025Trial
- A functional food approach: probiotic-fermentedFrontiers in nutrition · 2026Article
- The Exposome in Melasma: A Comprehensive Review of Etiology, Mechanisms, and Implications for Management.Clinical, cosmetic and investigational dermatology · 2026Review
- A study revealed the impact of gut microbiota on acne vulgaris: Evidence based on Mendelian randomization.Medicine · 2025Article
- Latin American consensus on the treatment of melasma.International journal of dermatology · 2025Review
- Effects of gut microbiota in breast cancer.Frontiers in oncology · 2025Review
- Investigation into skin physiological parameters and mocroflora characteristics of melasma population in Lhasa China.Frontiers in microbiology · 2025Article
- Microbial dysbiosis in melasma through community profiling.Frontiers in microbiomes · 2025Article
- Exploring the influencing factors on acne, melasma, and rosacea: A case-control study in China.Journal of cosmetic dermatology · 2024Article
- Impact of microbiota on breast cancer hormone therapy.Cell stress · 2023Article
- New Mechanistic Insights of Melasma.Clinical, cosmetic and investigational dermatology · 2023Review
- Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, many studies have shown that the gut microbiota can affect the occurrence and development of a variety of human diseases. A variety of skin diseases are related to the regulation of the gut-skin axis, such as psoriasis, atopic dermatitis, and acne. Gut microbial dysbiosis can promote the development of these diseases. The gut microbiota can affect estrogen metabolism, β-glucuronidase secreted by the gut microbiota can promote the reabsorption of estrogen by the gut, and estrogen is transported to other parts of the body through the circulatory system. The occurrence and development of melasma are closely related to abnormal metabolism of estrogen. The relationship between the structure of the gut microbiota and melasma remains unclear. Epidemiological surveys were conducted in patients with melasma and healthy subjects (control group) in this study. The feces were collected for 16S rRNA sequencing analysis of the gut microbiota. To compare the similarities and differences in species diversity of the gut microbiota between these two groups, we calculated the α-diversity and β-diversity indices and analyzed the differences between them. We found that the abundance of
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.