ArticleFrontiers in microbiology2022
Diarrhea in suckling lambs is associated with changes in gut microbiota, serum immunological and biochemical parameters in an intensive production system.
Article in Frontiers in microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Reduced gut microbiota-derived indole-3-carboxaldehyde and 5-hydroxyindole-3-acetic acid are associated with intestinal barrier dysfunction and inflammation in diarrheic suckling lambs.Journal of animal science and biotechnology · 2026Article
- Case series of neonatal lamb diarrhea syndrome treated with an evidence-based protocol to reduce antibacterial use.Veterinary research communications · 2026Article
- Epidemiological and Metabolic Characteristics ofAnimals : an open access journal from MDPI · 2026Article
- Dynamic Shifts in Gut Microbiota and Metabolic Pathways of Xinggao Mutton Sheep During Weaning: A Multi-Omics Analysis.Animals : an open access journal from MDPI · 2026Article
- Cecropin AD improves growth performance in impaired lambs by modulating gastrointestinal morphology, barrier function, and microbial composition.BMC veterinary research · 2026Article
- Article
- Impacts of Early Weaning on Lamb Gut Health and Immune Function: Short-Term and Long-Term Effects.Animals : an open access journal from MDPI · 2025Article
- Growth Characteristics of Sheep-DerivedMicroorganisms · 2025Article
- Yeast peptides alleviate diarrhea in neonatal lambs by enhancing the colonic barrier function and modulating colonic microbiota.Frontiers in veterinary science · 2025Article
- DietaryFrontiers in microbiomes · 2025Article
- Effects of Spent Substrate of Oyster Mushroom (Animals : an open access journal from MDPI · 2024Article
- Therapeutic potential of compound extract from Dracocephalum Rupestre Hance and Berberidis Radix against Salmonella-induced lamb diarrhea.Scientific reports · 2024Article
- Nucleotide sequence variants, gene expression and serum profile of immune and antioxidant markers associated with bacterial diarrhea susceptibility in Barki lambs.BMC veterinary research · 2024Article
- Unveiling genetic signatures associated with resilience to neonatal diarrhea in lambs through two GWAS approaches.Scientific reports · 2024Article
- Article
- Prickly ash seeds can promote healthy production of sheep by regulating the rumen microbial community.Frontiers in microbiology · 2024Article
- Integrated Small Intestine Microbiota and Serum Metabolomics Reveal the Potential Mechanisms of Wine Steaming in Alleviating Rhubarb-Induced Diarrhea.Journal of inflammation research · 2024Article
- Combining 16S rRNA Sequencing and Metabolomics Data to Decipher the Interactions between Gut Microbiota, Host Immunity, and Metabolites in Diarrheic Young Small Ruminants.International journal of molecular sciences · 2023Article
- Prickly Ash Seeds improve immunity of Hu sheep by changing the diversity and structure of gut microbiota.Frontiers in microbiology · 2023Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of diarrhea in lambs is frequent in large-scale sheep farms, which greatly impacts the growth and health of lambs. The aim of this study was to assess the changes in serum biochemical and immunological parameters and gut microbiome composition in suckling lambs suffering from diarrhea or not, reared on an intensive commercial farm. We found a reduced diversity of intestinal bacteria in suckling lambs suffering from diarrhea. Firmicutes and Bacteroidetes were the dominant flora in both groups of lambs, while the Bacteroidetes decreased in diarrheic lambs, no changes were reported in Firmicutes. Compared with healthy lambs, the proportion of aerobic bacteria, facultative anaerobic bacteria, and stress tolerant bacteria increased in lambs suffering from diarrhea, while that of anaerobic bacteria and potentially pathogenic bacteria decreased slightly. In addition, the contents of total cholesterol, immunoglobulins (Ig) G, and IgM in the serum of lambs suffering from diarrhea were lower than those of healthy lambs. This study explored the association between diarrhea occurrence, intestinal microbial community structure, and metabolic and immunological status in Hu lambs.
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