ArticleFrontiers in aging neuroscience2022
The moderating effect of cognitive reserve on cognitive function in patients with Acute Ischemic Stroke.
Article in Frontiers in aging neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Guidelines for Neuroprognostication in Critically ill Adults with Acute Ischemic Stroke.Neurocritical care · 2026Guideline
- Epidemiology and Outcomes Associated with Cognitive Frailty and Reserve in a Stroke Population: Systematic Review and Meta-Analysis.Cerebrovascular diseases (Basel, Switzerland) · 2025Pooled it
- Short-term Trajectories of Poststroke Cognitive Function: A STROKOG Collaboration Study.Neurology · 2023Pooled it
- Analysis of Predictive Factors for Cognitive Function Improvement After tDCS Treatment in Patients With Post-stroke Cognitive Impairment.Actas espanolas de psiquiatria · 2026Article
- Age, race, and education as moderators of post-stroke cognitive decline following dental care.Frontiers in stroke · 2026Article
- How to Improve Cognitive Flexibility: Evidence From Noninvasive Neuromodulation Techniques.CNS neuroscience & therapeutics · 2025Review
- Commentary on "The effects of moderate-intensity aerobic exercise on cognitive function in individuals with stroke-induced mild cognitive impairment: a randomized controlled pilot study".Journal of rehabilitation medicine · 2025Article
- Functional Connectivity and MRI Radiomics Biomarkers of Cognitive and Brain Reserve in Post-Stroke Cognitive Impairment Prediction-A Study Protocol.Life (Basel, Switzerland) · 2025Article
- Improving Post-Stroke Cognitive Impairment via Cognitive and Motor Dual Task Gait Training: Potential Mechanisms and Clinical Value.Neuropsychiatric disease and treatment · 2025Review
- Is cognitive reserve associated with cognitive function across stroke severity? A longitudinal study among Chinese stroke patients.Frontiers in aging neuroscience · 2025Article
- Analytical cohort study on cognitive reserve as a predictor of post-stroke dementia severity.Bioinformation · 2025Article
- Risk factors and predictive markers of post-stroke cognitive decline-A mini review.Frontiers in aging neuroscience · 2024Review
- Influence of Age, Gender and Education Level on Executive Functions and Functioning in People with Stroke.Biomedicines · 2023Article
- The clinical and neurocognitive functional changes with awake brain mapping for gliomas invading eloquent areas: Institutional experience and the utility of The Montreal Cognitive Assessment.Frontiers in oncology · 2023Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Background: Recovery of cognitive function after stroke has inter-individual variability. The theory of cognitive reserve offers a potential explanation of the variability in cognitive function after stroke. Objective: This study aimed to investigate the moderating effect of cognitive reserve on the relationship between the stroke severity and cognitive function after stroke. Materials and methods: A total of 220 patients with Acute Ischemic Stroke (AIS) were recruited in 2021 from two stroke centers in Nanjing, China. The National Institutes of Health Stroke Scale (NIHSS) was used to assess stroke severity upon admission. Cognitive Reserve Index questionnaire (CRIq) and validated Montreal Cognitive Assessment, Changsha Version (MoCA-CS) were used to assess cognitive reserve and cognitive function within 7 days after stroke onset, respectively. A series of multivariate linear regression models were applied to test the moderating effect of cognitive reserve. Results: Patients with a higher level of cognitive reserve had better cognitive function after stroke compared with those with a lower level of cognitive reserve (β = 0.074, Conclusion: Cognitive reserve may help to buffer the effect of stroke-related pathology on cognitive decline in Chinese acute stroke patients. Enhancing cognitive reserve in stroke patients may be one of the potential strategies for preventing vascular dementia.
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