Evidence map›Paper›PMID 36466434›Full record

Trial reportQatar medical journal2022

Risk factors associated with chronic kidney disease progression: Long-term retrospective analysis from Qatar.

Ahmed Farouk Hamdi, Ashraf Fawzy, Essa Abuhelaiqa, Muhammad Asim, Awais Nuaman, Adel Ashur, Omar Fituri, Mohamad Alkadi, Hassan Al-Malki

Open access · diamondAbstract readClinical Trial
In one paragraph

Trial report in Qatar medical journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Ahmed Farouk HamdiHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Ashraf FawzyHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Essa AbuhelaiqaHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Muhammad AsimHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Awais NuamanHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Adel AshurHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Omar FituriHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Mohamad AlkadiHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
Hassan Al-MalkiHamad General Hospital, Hamad Medical Corporation, Qatar. Email and ORCID ID: ahamdi@hamad.qa & https://orcid.org/0000-0002-7289-4942.
ORCID · USHamad General Hospital · QAHamad Medical Corporation · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe risk factors influencing the natural course of chronic kidney disease (CKD) are complex and heterogeneous. Recognizing the factors associated with CKD progression can enable the identification of high-risk patients for more intensive treatment. PATIENTS AND

methodsA retrospective evaluation of CKD patients was performed under follow-up between January 1, 2001 and December 31, 2016 at a tertiary health care center.

resultsAmong 5370 screened patients, 1020 patients with complete data were included in the analysis. The median follow-up period for the studied patients was 9.3 years. Based on the analysis, 120 (11.8%) patients had reached end-stage kidney disease "ESKD" or death. The study revealed that the risk factors associated with reaching ESKD and/or death using Kaplan-Meier survival curve and log rank test included higher hemoglobin A1c among diabetic patients, higher grade of proteinuria, and non use of renin-angiotensin system blockers. The patients with CKD progression constituted 77.2% of all CKD patients. The study findings indicated that older age, Arab ethnicity, smoking habit, diabetes mellitus and hypertension (presumed as original kidney diseases) are among the significant risk factors associated with a further decline of the estimated glomerular filtration rate (eGFR) and further CKD progression.

conclusionThis study summarized the demographic and clinical risk factors associated with CKD progression and patients' outcomes among a unique and heterogeneous population in the state of Qatar. Intensive treatment of modifiable risk factors could be of value in halting the progression of CKD. However, prospective studies are warranted to confirm our findings.

Indexed as

chronic kidney diseaseend-stage kidney diseaseprogression risk factors

Identifiers

PMID36466434
PMCPMC9713692
OpenAlexW4310783784

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.