Evidence map›Paper›PMID 36466348›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Amnion and chorion matrix maintain hMSC osteogenic response and enhance immunomodulatory and angiogenic potential in a mineralized collagen scaffold.

Vasiliki Kolliopoulos, Marley J Dewey, Maxwell Polanek, Hui Xu, Brendan A C Harley

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vasiliki KolliopoulosChemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, IL, United States.
Marley J DeweyDepartment Materials Science and Engineering, University of Illinois at Urbana-Champaign, IL, United States.
Maxwell PolanekChemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, IL, United States.
Hui XuTumor Engineering and Phenotyping (TEP) Shared Resource, Cancer Center at Illinois, University of Illinois Urbana-Champaign, Urbana, IL, United States.
Brendan A C HarleyChemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, IL, United States.
University of Illinois Urbana-Champaign · USUrbana University · US

Funding

Training Program in Chemistry-Interface with BiologyT32GM070421 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI HERGENROTHER, PAUL · 2005 to 2019
$5.4M
Training Program at the Chemistry Biology InterfaceT32GM136629 · NIGMS · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI Paul Hergenrother · 2020 to 2026
$4.5M
Mineralized collagen composite to accelerate craniofacial bone regenerationR01DE030491 · NIDCR · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HARLEY, BRENDAN A. · 2021 to 2025
$2.2M
Amniotic Membrane Derived Matrix for Large Bone Defect RepairR21DE026582 · NIDCR · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI HARLEY, BRENDAN A., WHEELER, MATTHEW B · 2018 to 2019
$660k
NIDCR NIH HHS R01 DE030491NIDCR NIH HHS R21 DE026582NIGMS NIH HHS T32 GM070421NIGMS NIH HHS T32 GM136629
6 · The paper itself

Abstract

Craniomaxillofacial (CMF) bone injuries present a major surgical challenge and cannot heal naturally due to their large size and complex topography. We are developing a mineralized collagen scaffold that mimics extracellular matrix (ECM) features of bone. These scaffolds induce

Indexed as

amnion membranebone regenerationchorion membranecollagen scaffoldcraniomaxillofacial defects

Identifiers

PMID36466348
PMCPMC9714677
OpenAlexW4309043324

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.