Evidence map›Paper›PMID 36466231›Full record

ArticleFrontiers in plant science2022

Efficient virus-mediated genome editing in cotton using the CRISPR/Cas9 system.

Jianfeng Lei, Yue Li, Peihong Dai, Chao Liu, Yi Zhao, Yangzi You, Yanying Qu, Quanjia Chen, Xiaodong Liu

Abstract read
In one paragraph

Article in Frontiers in plant science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. CRISPR-Cas9-Mediated Knockout ofPlants (Basel, Switzerland) · 2025
    Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Intein-mediated splitFrontiers in genome editing · 2024
    Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jianfeng LeiCollege of Agriculture, Xinjiang Agricultural University, Engineering Research Centre of Cotton, Ministry of Education, Urumqi, China.
Yue LiCollege of Life Sciences, Xinjiang Agricultural University, Urumqi, China.
Peihong DaiCollege of Life Sciences, Xinjiang Agricultural University, Urumqi, China.
Chao LiuCollege of Life Sciences, Xinjiang Agricultural University, Urumqi, China.
Yi ZhaoCollege of Life Sciences, Xinjiang Agricultural University, Urumqi, China.
Yangzi YouCollege of Life Sciences, Xinjiang Agricultural University, Urumqi, China.
Yanying QuCollege of Agriculture, Xinjiang Agricultural University, Engineering Research Centre of Cotton, Ministry of Education, Urumqi, China.
Quanjia ChenCollege of Agriculture, Xinjiang Agricultural University, Engineering Research Centre of Cotton, Ministry of Education, Urumqi, China.
Xiaodong LiuCollege of Life Sciences, Xinjiang Agricultural University, Urumqi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plant virus-mediated sgRNA delivery and expression have great advantages; sgRNA expression can rapidly expand and accumulate along with virus replication and movement, resulting in efficient gene editing efficiency. In this study, a VIGE system based on cotton leaf crumple virus (CLCrV) was established using cotton overexpressing Cas9 (Cas9-OE) as the VIGE receptor. CLCrV-mediated VIGE could not only target and knock out the

Indexed as

Cas9-OECLCrVcottonFT-sgRNAmutationVIGE

Identifiers

PMID36466231
PMCPMC9709312

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.