Evidence map›Paper›PMID 36466104›Full record

ArticleEuroasian journal of hepato-gastroenterology2022

Comparison of Clinical, Biochemical, and Histopathologic Profiles between NAFLD in Asian-Indians and United States Adults.

Shivaram P Singh, Manas K Panigrahi, Anish Patel, Lavanya Viswanathan, Mitali M Rath, Sanjib K Kar, Stephen A Harrison

Open access · diamondAbstract read
In one paragraph

Article in Euroasian journal of hepato-gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 3 countries.

Shivaram P SinghDepartment of Gastroenterology, SCB Medical College, Cuttack, Odisha, India.
Manas K PanigrahiDepartment of Gastroenterology, AIIMS, Bhubaneswar, Odisha, India.
Anish PatelDepartment of Gastroenterology and Hepatology, Brooke Army Medical Center, San Antonio, Texas, United States of America.
Lavanya ViswanathanDepartment of Gastroenterology and Hepatology, David Grant Medical Center, Fairfield, California, United States of America.
Mitali M RathDepartment of Pathology, Hi-Tech Medical College and Hospital, Bhubaneswar, Odisha, India.
Sanjib K KarDepartment of Gastroenterology, Gastro Liver Care, Cuttack, Odisha, India.
Stephen A HarrisonDepartment of Medicine, University of Oxford, Oxford, United Kingdom.
All India Institute of Medical Sciences Bhubaneswar · INDavid Grant USAF Medical Center · USHi-Tech Medical College & Hospital · INSriram Chandra Bhanja Medical College Hospital · INUniversity of Oxford · GBWilford Hall Ambulatory Surgical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Nonalcoholic fatty liver disease (NAFLD) is very common in both Asian and Western countries. Geographic variation leads to differences in epidemiological and demographic characters of NAFLD patients. Studies conducted upon different ethnic groups in the United States (US) show a higher prevalence of NAFLD in Hispanics and African-Americans. There is however, a paucity of studies involving Asians. It has been observed that Asian-Indian NAFLD patients have unique characteristics compared to their counterparts in the West. This study is the first attempt at comparing the characteristics of Asian-Indian and US NAFLD patients. Materials and Methods: A retrospective analysis of clinical, biochemical, and histological data was performed for 633 Asian-Indian NAFLD patients and 451 US NAFLD patients. Clinical parameters [age, gender, body mass index (BMI), diabetes, hypertension, etc.], biochemical tests (liver function tests, lipid profile, and fasting blood sugar), hepatic ultrasound and hepatic histology were compared between the two cohorts. Results: Eighty-two percent of US NAFLD patients were more than 40 years of age compared to 51.3% of Asian-Indian patients ( Conclusion: Asian-Indian and US NAFLD patients differ significantly on several parameters. Further studies need to be carried out to understand the mechanistic basis of these differences better. How to cite this article: Singh SP, Panigrahi MK, Patel A,

Indexed as

EpidemiologyEthnicityEthnologyNAFLDNonalcoholic fatty liver diseaseNonalcoholic steatohepatitis

Identifiers

PMID36466104
PMCPMC9681572
OpenAlexW4297830827

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.