Evidence map›Paper›PMID 36466090›Full record

ArticleOxidative medicine and cellular longevity2022

Microbiome-Metabolome Analysis of the Immune Microenvironment of the Cecal Contents, Soft Feces, and Hard Feces of Hyplus Rabbits.

Zhichao Li, Hui He, Mengke Ni, Zhouyan Wang, Chaohui Guo, Yufang Niu, Shanshan Xing, Mingkun Song, Yaling Wang, Yixuan Jiang and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2025
    Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. International journal of molecular sciences · 2023
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Zhichao LiCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-5448-9145
Hui HeCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-5012-494X
Mengke NiCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-5741-6600
Zhouyan WangHenan University of Chinese Medicine, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-3154-5690
Chaohui GuoCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-5041-9887
Yufang NiuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-5752-6570
Shanshan XingCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-5285-0726
Mingkun SongCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-1934-1919
Yaling WangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-7093-9214
Yixuan JiangCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0001-5767-0206
Lei YuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-5293-1339
Ming LiCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0002-2218-4408
Huifen XuCollege of Animal Science and Technology, Henan Agricultural University, Zhengzhou 450046, China.ORCID https://orcid.org/0000-0003-3963-2868
Henan Agricultural University · CNFirst Affiliated Hospital of Henan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The intestinal microbiota and its metabolites play vital roles in host growth, development, and immune regulation. This study analyzed the microbial community distribution and the cytokine and short-chain fatty acid (SCFA) content of cecal contents (Con group), soft feces (SF group), and hard feces (HF group) of 60-day-old Hyplus rabbits and verified the effect of soft feces on the cecal immune microenvironment by coprophagy prevention (CP). The results showed that there were significant differences in the levels of phylum and genus composition, cytokines, and SCFAs among the Con group, SF group, and HF group. The correlation analysis of cytokines and SCFAs with differential microbial communities showed that

Indexed as

CecumMicrobiotaAnimalsButyric AcidCytokinesFecesMetabolomeRabbitsButyric AcidCytokines

Identifiers

PMID36466090
PMCPMC9713467
OpenAlexW4307650795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.