Evidence map›Paper›PMID 36465906›Full record

ArticleFrontiers in medicine2022

Hospital-acquired bloodstream infections in patients deceased with COVID-19 in Italy (2020-2021).

Monica Monaco, Marco Floridia, Marina Giuliano, Luigi Palmieri, Cinzia Lo Noce, Annalisa Pantosti, Anna Teresa Palamara, Silvio Brusaferro, Graziano Onder, Italian National Institute of Health COVID-19 Mortality Group

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Observational
  2. Review
  3. Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Monica MonacoDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Marco FloridiaNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Marina GiulianoNational Center for Global Health, Istituto Superiore di Sanità, Rome, Italy.
Luigi PalmieriDepartment of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Rome, Italy.
Cinzia Lo NoceDepartment of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Rome, Italy.
Annalisa PantostiDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Anna Teresa PalamaraDepartment of Infectious Diseases, Istituto Superiore di Sanità, Rome, Italy.
Silvio BrusaferroOffice of the President, Istituto Superiore di Sanità, Rome, Italy.
Graziano OnderDepartment of Cardiovascular, Endocrine-Metabolic Diseases and Aging, Istituto Superiore di Sanità, Rome, Italy.
Italian National Institute of Health COVID-19 Mortality Group
Istituto Superiore di Sanità · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: In hospitalized patients with COVID-19, bloodstream infections (BSI) are associated with high mortality and high antibiotic resistance rates. The aim of this study was to describe BSI etiology, antimicrobial resistance profile and risk factors in a sample of patients deceased with COVID-19 from the Italian National COVID-19 surveillance. Methods: Hospital charts of patients who developed BSI during hospitalization were reviewed to describe the causative microorganisms and their antimicrobial susceptibility profiles. Risk factors were analyzed in univariate and multivariate analyses. Results: The study included 73 patients (71.2% male, median age 70): 40 of them (54.8%) received antibiotics and 30 (41.1%) systemic steroids within 48 h after admission; 53 (72.6%) were admitted to intensive care unit. Early steroid use was associated with a significantly shorter interval between admission and BSI occurrence. Among 107 isolated microorganisms, the most frequent were Conclusions: In patients deceased with COVID-19, a large proportion of BSI are caused by antibiotic-resistant bacteria. Early steroid use may facilitate this occurrence.

Indexed as

antimicrobial resistancebacterial infectionsbloodstream infectionsCOVID-19fungal infectionssecondary infections

Identifiers

PMID36465906
PMCPMC9713028
OpenAlexW4309609244

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.