Evidence map›Paper›PMID 36465819›Full record

ArticleQuantitative imaging in medicine and surgery2022

Interval changes of histogram-derived diffusion indices predict treatment response to induction chemotherapy in head and neck cancer: a feasibility study.

Kai-Lun Cheng, Hsueh-Ju Lu, Xi Lin, Hui-Yu Wang, Ying-Hsiang Chou, Yeu-Sheng Tyan, Ping-Huei Tsai

Open access · diamondAbstract read
In one paragraph

Article in Quantitative imaging in medicine and surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Kai-Lun ChengDepartment of Medical Imaging, Chung Shan Medical University Hospital, Taichung.
Hsueh-Ju LuDivision of Hematology and Oncology, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung.
Xi LinDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung.
Hui-Yu WangDepartment of Medical Imaging, Chung Shan Medical University Hospital, Taichung.
Ying-Hsiang ChouDepartment of Medical Imaging and Radiological Sciences, Chung Shan Medical University, Taichung.
Yeu-Sheng TyanDepartment of Medical Imaging, Chung Shan Medical University Hospital, Taichung.
Ping-Huei TsaiDepartment of Medical Imaging, Chung Shan Medical University Hospital, Taichung.
Chung Shan Medical University Hospital · TWChung Shan Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: This retrospective study investigated whether the interval change of apparent diffusion coefficient (∆ADC) [baseline and after the first cycle of induction chemotherapy (ICT)] can be used as a valid predictive imaging biomarker of the treatment response to ICT in head and neck cancer (HNC). Methods: A total of 19 consecutive patients with HNC who underwent diffusion-weighted magnetic resonance imaging (DWI) at baseline and after the first cycle of ICT were included. Whole-tumor ADC histogram parameters (mean, median, kurtosis, skewness, entropy, minimal, maximum, 25th percentile, and 75th percentile) were obtained. The correlations of ∆ADC histogram parameters, volume, T-stage, N-stage, and age with the treatment response were examined using the Mann-Whitney U test. The predictive value of histogram parameters was examined using receiver operating characteristic (ROC) curves. Results: Responders showed significantly higher values of ∆ADC Conclusions: ∆ADC

Indexed as

diffusionHead and neck cancer (HNC)histogrammagnetic resonance imaging (MRI)

Identifiers

PMID36465819
PMCPMC9703116
OpenAlexW4294693718

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.