Evidence map›Paper›PMID 36465810›Full record

ReviewInfection and drug resistance2022

Progress in Multidisciplinary Treatment of Fournier's Gangrene.

Ke-Fan Zhang, Chuan-Xin Shi, Si-Yu Chen, Wei Wei

Open access · goldAbstract readReview
In one paragraph

Review in Infection and drug resistance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
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  4. Article
  5. Surgical fecal diversionWorld journal of critical care medicine · 2026
    Article
  6. Rehabilitation Evaluation and Treatment for Skin Graft Complications of the Genitalia.Journal of burn care & research : official publication of the American Burn Association · 2026
    Article
  7. Article
  8. Article
  9. Article
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  11. Observational
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  14. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ke-Fan Zhang *Department of General Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Chuan-Xin Shi *Department of General Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.
Si-Yu Chen *Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0002-7423-012X
Wei WeiDepartment of General Surgery, The Second Affiliated Hospital of Nanjing Medical University, Nanjing, People's Republic of China.ORCID 0000-0002-6734-5623
Second Affiliated Hospital of Nanjing Medical University · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fournier's gangrene (FG) is a life-threatening and special form of necrotizing fasciitis, characterized by occult onset, rapid progress and high mortality, occurring mainly in men over 50 years of age. Risk factors of FG include diabetes, HIV infection, chronic alcoholism and other immunosuppressive state. FG was previously considered as an idiopathic disease, but in fact, three quarters of the infections originated from the skin, urethra and gastrointestinal tract. Initial symptoms of FG are often inconsistent with severity and can progress promptly to fatal infection. Although the treatment measures of FG have been improved in recent years, the mortality does not seem to have decreased significantly and remains at 20% - 30%. The time to identify FG and the waiting period before surgical debridement are directly related to the prognosis. Therefore, in addition to the combination of intensive fluid resuscitation and broad-spectrum antibiotics, treatment of FG should particularly emphasize the importance of early surgical debridement assisted with fecal diversion and skin reconstruction when necessary. This paper is to briefly summarize the progress in the definition, epidemiology, clinical manifestations, diagnosis, treatment and prognosis of Fournier's gangrene in recent years, more importantly, illustrates the importance of multidisciplinary cooperation in the management of FG.

Indexed as

Fournier’s gangrenelethal infectionmultidisciplinary cooperationnecrotizing fasciitissurgical debridement

Identifiers

PMID36465810
PMCPMC9717591
OpenAlexW4310252799

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.