ArticleCureus2022
Recalcitrant Fungal Corneal Ulcer.
Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
- Current Challenges and Long-Term Outcomes in Corneal Transplantation in Infectious Keratitis-A Systematic Review.Journal of clinical medicine · 2026Review
- Establishment of a corneal ulcer prognostic model based on machine learning.Scientific reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cornea forms the major refracting surface of the eye. Any disease affecting the cornea leads to severe visual impairment. One of the most common pathologies affecting the cornea is infective keratitis. In India, especially in rural areas, infective corneal ulcers are major causes of visual impairment. Medical therapy with antimicrobial medicines is usually started first and if fails to heal the ulcer or there is progressive corneal thinning or corneal perforation then surgical treatments like penetrating keratoplasty are the only modality to salvage the globe integrity. Fungal keratitis particularly in tropical and subtropical areas has a poor prognosis as compared to bacterial keratitis. The main reasons for poor outcomes are delayed diagnosis and a lack of effective antifungal therapies. Over the last decade, significant advances have been made in quick diagnosis in cases of mycotic keratitis and also effective medical treatment. We report a case of a 56-year-old female who was diagnosed with left eye fungal corneal ulcer on systemic and topical antifungal agents for the last two months. She presented to us with an increase in pain, watering, and redness in her left eye for the past two days. On examination, the patient had desmetocele with impending perforation. The patient was advised to undergo therapeutic penetrating keratoplasty in her left eye. Penetrating keratoplasty plays a crucial part in eyes with refractory keratitis, impending perforation, or eyes with corneal perforation. Penetrating keratoplasty in such cases helps to replace the diseased tissue, decrease the infective load, and also helps to restore anatomical integrity of the globe and usable eyesight with good success rate. Early intervention prior to perforation or limbal/scleral extension can lead to better results at least in maintaining the globe integrity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.