Evidence map›Paper›PMID 36465700›Full record

ArticleAdvances in pharmacological and pharmaceutical sciences2022

Cytotoxic and Antioxidant Properties of Natural Bioactive Monoterpenes Nerol, Estragole, and 3,7-Dimethyl-1-Octanol.

Mayara Ladeira Coêlho, Muhammad Torequl Islam, George Laylson da Silva Oliveira, Marcus Vinicius Oliveira Barros de Alencar, José Victor de Oliveira Santos, Antonielly Campinho Dos Reis, Ana Maria Oliveira Ferreira da Mata, Márcia Fernanda Correia Jardim Paz, Anca Oana Docea, Daniela Calina and 2 more

Open access · goldAbstract read
In one paragraph

Article in Advances in pharmacological and pharmaceutical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Evaluation Profile of SicilianPlants (Basel, Switzerland) · 2026
    Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Nerol as a Novel Antifungal Agent: In Vitro Inhibitory Effects onJournal of fungi (Basel, Switzerland) · 2024
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 4 countries.

Mayara Ladeira CoêlhoNortheast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, Brazil.
Muhammad Torequl IslamDepartment of Pharmacy, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj 8100, Bangladesh.
George Laylson da Silva OliveiraNortheast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, Brazil.
Marcus Vinicius Oliveira Barros de AlencarNortheast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, Brazil.
José Victor de Oliveira SantosPost-Graduation Program in Pharmaceutical Science, Federal University of Piauí, Teresina, Brazil.
Antonielly Campinho Dos ReisIntegral Diferencial College (FACID-DEVRY), Teresina, Piaui, Brazil.
Ana Maria Oliveira Ferreira da MataPost-Graduation Program in Pharmaceutical Science, Federal University of Piauí, Teresina, Brazil.
Márcia Fernanda Correia Jardim PazNortheast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, Brazil.
Anca Oana DoceaDepartment of Toxicology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Daniela CalinaDepartment of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID https://orcid.org/0000-0002-1523-9116
Javad Sharifi-RadFacultad de Medicina, Universidad del Azuay, Cuenca, Ecuador, Iran.ORCID https://orcid.org/0000-0002-7301-8151
Ana Amélia de Carvalho Melo-CavalcanteNortheast Biotechnology Network (RENORBIO), Federal University of Piauí, Teresina, Brazil.
Universidade Federal do Piauí · BRUniversity of Medicine and Pharmacy of Craiova · ROGopalganj Science and Technology University · BDUniversidad del Azuay · EC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The therapeutic potential of medicinal plants is noted because of the presence of varieties of biochemicals. The monoterpenes, like nerol, estragole, and 3,7-dimethyl-1-octanol, have been reported for antimicrobial, antifungal, anthelmintic, and antioxidant activities. This study evaluated the toxic, cytotoxic, and oxidant/antioxidant effects of these compounds by several in vitro (DPPH and ABTS radical scavenging, and ferric reducing potential), ex vivo (hemolysis), and in vivo (

Identifiers

PMID36465700
PMCPMC9712021
OpenAlexW4309902974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.