ReviewFrontiers in endocrinology2022
An update of the consensus statement on insulin resistance in children 2010.
Review in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Premature adrenarche and metabolic risk: a systematic review and meta-analysis.European journal of endocrinology · 2025Pooled it
- Assessing the Diagnostic Performance of Triglyceride-Glucose-Based Indices for Early Detection of Metabolic Syndrome in Paediatric Down Syndrome.Journal of intellectual disability research : JIDR · 2026Article
- Metabolic Dysfunction-Associated Steatotic Liver Disease in Childhood: From Disease Heterogeneity to Personalized Care.Journal of personalized medicine · 2026Review
- Development and external validation of machine learning models to predict insulin resistance among iron-deficient children and adolescents.Translational pediatrics · 2026Article
- Combined Effects of Mediterranean Diet Adherence and Physical Activity on Metabolic Homeostasis and Beta-Cell Function in Male Adolescents.Nutrients · 2026Observational
- Assessment of BMI percentages of obesity thresholds and cardiometabolic risk factors in children and adolescents: a retrospective cross-sectional study in Beijing.Lipids in health and disease · 2026Article
- Diagnostic Accuracy of the Triglyceride-Glucose Derived Indices in Detecting Metabolic Syndrome in Pediatric Patients.Journal of obesity & metabolic syndrome · 2026Article
- Beyond metabolism: nutrition, sleep, and psychological wellbeing in children with insulin resistance-a case-control study.Frontiers in nutrition · 2026Article
- Adipokine, endocrine, and fibrinolysis-related alterations across abdominal obesity and metabolic syndrome phenotypes in young adults.Frontiers in endocrinology · 2026Article
- An Altered Lipid Profile Is Indicative of Increased Insulin Requirement in Children and Adolescents at the Onset of Type 1 Diabetes.Journal of personalized medicine · 2026Article
- Erythrocyte membrane lipid profile in children and adolescents with metabolic dysfunction-associated steatotic liver disease and insulin resistance: a preliminary study.Scientific reports · 2025Article
- Lifestyle intervention improves cardiometabolic profiles among children with metabolically healthy and metabolically unhealthy obesity.Diabetology & metabolic syndrome · 2024Article
- The associations of insulin resistance, obesity, and lifestyle with the risk of developing hyperuricaemia in adolescents.BMC endocrine disorders · 2024Article
- Identifying metabotypes of insulin resistance severity in children with metabolic syndrome.Cardiovascular diabetology · 2024Article
- DXA-based Fat Mass With Risk of Worsening Insulin Resistance in Adolescents: A 9-Year Temporal and Mediation Study.The Journal of clinical endocrinology and metabolism · 2024Article
- Article
- Not Only Metabolic Complications of Childhood Obesity.Nutrients · 2024Review
- [Value of C-peptide-based insulin resistance index for evaluating correlation between insulin resistance and serum uric acid level in individuals undergoing health examination].Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2023Article
- G Protein-Coupled Receptors and the Rise of Type 2 Diabetes in Children.Biomedicines · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In our modern society, where highly palatable and calorie-rich foods are readily available, and sedentary lifestyle is common among children and adolescents, we face the pandemic of obesity, nonalcoholic fatty liver disease, hypertension, atherosclerosis, and T2D. Insulin resistance (IR) is known to be the main underlying mechanism of all these associated health consequences; therefore, the early detection of IR is fundamental for preventing them.A Consensus Statement, internationally supported by all the major scientific societies in pediatric endocrinology, was published in 2010, providing all the most recent reliable evidence to identify the definition of IR in children, its measurement, its risk factors, and the effective strategies to prevent and treat it. However, the 2010 Consensus concluded that further research was necessary to assess some of the discussed points, in particular the best way to measure insulin sensitivity, standardization of insulin measurements, identification of strong surrogate biomarkers of IR, and the effective role of lifestyle intervention and medications in the prevention and treatment of IR.The aim of this review is to update each point of the consensus with the most recent available studies, with the goal of giving a picture of the current state of the scientific literature regarding IR in children, with a particular regard for issues that are not yet fully clarified.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.