Evidence map›Paper›PMID 36465633›Full record

ArticleFrontiers in endocrinology2022

A spatiotemporal steroidogenic regulatory network in human fetal adrenal glands and gonads.

Yifu Wang, Bingqian Guo, Yajie Guo, Nana Qi, Yufang Lv, Yu Ye, Yan Huang, Xinyang Long, Hongfei Chen, Cheng Su and 14 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Biomimetic Gland Models with Engineered Stratagems.Research (Washington, D.C.) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 3 institutions in 1 country.

Yifu WangCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Bingqian GuoCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yajie GuoCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Nana QiCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yufang LvCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yu YeCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yan HuangDepartment of Obstetrics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Xinyang LongCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Hongfei ChenDepartment of Obstetrics, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Cheng SuCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Liying ZhangDepartment of Gynecology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Qingyun ZhangCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Minxi LiDepartment of Gynecology, The Second Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, China.
Jinling LiaoCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yunkun YanCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Xingning MaoCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yanyu ZengCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Jinghang JiangCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Zhongyuan ChenCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yi GuoCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Shuai GaoCollege of Animal Science and Technology, China Agricultural University, Beijing, China.
Jiwen ChengCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Yonghua JiangCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Zengnan MoCenter for Genomic and Personalized Medicine, Guangxi Medical University, Nanning, Guangxi, China.
Guangxi Medical University · CNFirst Affiliated Hospital of GuangXi Medical University · CNChina Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human fetal adrenal glands produce substantial amounts of dehydroepiandrosterone (DHEA), which is one of the most important precursors of sex hormones. However, the underlying biological mechanism remains largely unknown. Herein, we sequenced human fetal adrenal glands and gonads from 7 to 14 gestational weeks (GW)

Indexed as

FetusGonadsAdrenal GlandsDehydroepiandrosteroneFemaleHumansMaleSex DifferentiationDehydroepiandrosteroneadrenal glandsSc-RNA sequencingsexual differentiationspatial transcriptomicssteroidogenic regulation network

Identifiers

PMID36465633
PMCPMC9713933
OpenAlexW4309606720

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.