Evidence map›Paper›PMID 36465529›Full record

ReviewJACS Au2022

3D-Printed Microarray Patches for Transdermal Applications.

Netra U Rajesh, Ian Coates, Madison M Driskill, Maria T Dulay, Kaiwen Hsiao, Dan Ilyin, Gunilla B Jacobson, Jean Won Kwak, Micah Lawrence, Jillian Perry and 3 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in JACS Au, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  15. High-resolution stereolithography: Negative spaces enabled by control of fluid mechanics.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
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  18. Toward Tunable Protein-Driven Hydrogel Lens.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Netra U RajeshDepartment of Bioengineering, Stanford University, Stanford, California94305, United States.
Ian CoatesDepartment of Chemical Engineering, Stanford University, Stanford, California94305, United States.
Madison M DriskillDepartment of Chemical Engineering, Stanford University, Stanford, California94305, United States.
Maria T DulayDepartment of Radiology, Stanford University, Stanford, California94305, United States.ORCID https://orcid.org/0000-0002-4678-3480
Kaiwen HsiaoDepartment of Chemical Engineering, Stanford University, Stanford, California94305, United States.
Dan IlyinDepartment of Mechanical Engineering, Stanford University, Stanford, California94305, United States.
Gunilla B JacobsonDepartment of Radiology, Stanford University, Stanford, California94305, United States.
Jean Won KwakDepartment of Radiology, Stanford University, Stanford, California94305, United States.
Micah LawrenceDepartment of Bioengineering, Stanford University, Stanford, California94305, United States.
Jillian PerryEshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina27599, United States.ORCID https://orcid.org/0000-0002-2837-8131
Cooper O SheaDepartment of Mechanical Engineering, Stanford University, Stanford, California94305, United States.
Shaomin TianDepartment of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina27599, United States.ORCID https://orcid.org/0000-0001-5220-3887
Joseph M DeSimoneDepartment of Chemical Engineering, Stanford University, Stanford, California94305, United States.ORCID https://orcid.org/0000-0001-9521-5095

Funding

Novel 3D printed microneedle patches for detection of viral infectionsR21EB029682 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LAKSHMANANE, PREMKUMAR, TIAN, SHAOMIN · 2020 to 2021
$428k
NIBIB NIH HHS R21 EB029682
6 · The paper itself

Abstract

The intradermal (ID) space has been actively explored as a means for drug delivery and diagnostics that is minimally invasive. Microneedles or microneedle patches or microarray patches (MAPs) are comprised of a series of micrometer-sized projections that can painlessly puncture the skin and access the epidermal/dermal layer. MAPs have failed to reach their full potential because many of these platforms rely on dated lithographic manufacturing processes or molding processes that are not easily scalable and hinder innovative designs of MAP geometries that can be achieved. The DeSimone Laboratory has recently developed a high-resolution continuous liquid interface production (CLIP) 3D printing technology. This 3D printer uses light and oxygen to enable a continuous, noncontact polymerization dead zone at the build surface, allowing for rapid production of MAPs with precise and tunable geometries. Using this tool, we are now able to produce new classes of lattice MAPs (L-MAPs) and dynamic MAPs (D-MAPs) that can deliver both solid state and liquid cargos and are also capable of sampling interstitial fluid. Herein, we will explore how additive manufacturing can revolutionize MAP development and open new doors for minimally invasive drug delivery and diagnostic platforms.

Identifiers

PMID36465529
PMCPMC9709783

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.