Evidence map›Paper›PMID 36465167›Full record

ReviewAging and disease2022

Exosomes as a Cell-free Therapy for Myocardial Injury Following Acute Myocardial Infarction or Ischemic Reperfusion.

Ziyu An, Jinfan Tian, Yue Liu, Xin Zhao, Xueyao Yang, Jingwen Yong, Libo Liu, Lijun Zhang, Wenjian Jiang, Xiantao Song and 1 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Aging and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ziyu An *1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jinfan Tian *1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Yue Liu2Cardiovascular disease center, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Xin Zhao1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xueyao Yang1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Jingwen Yong1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Libo Liu1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Lijun Zhang1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Wenjian Jiang3Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Xiantao Song1Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Hongjia Zhang3Department of Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Capital Medical University · CNBeijing Anzhen Hospital · CNChinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exosomes, which contain miRNA, have been receiving growing attention in cardiovascular therapy because of their role in mediating cell-cell communication, autophagy, apoptosis, inflammation, and angiogenesis. Several studies have suggested that miRNA derived from exosomes can be used to detect myocardial infarctions (MI) in patients. Basic research also suggests that exosomes could serve as a potential therapeutic target for treating acute myocardial infarction. Ischemia/reperfusion (IR) injury is associated with adverse cardiac events after acute MI. We aim to review the potential benefits and mechanisms of exosomes in treating MI and IR injury.

Indexed as

acute myocardial infarctioncell-free therapyexosomeischemic reperfusion

Identifiers

PMID36465167
PMCPMC9662265
OpenAlexW4310774821

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.