ArticleNeuropsychiatric disease and treatment2022
Effect of Personality Traits on Sustained Remission Among Patients with Major Depression: A 12-Month Prospective Study.
Article in Neuropsychiatric disease and treatment, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Improvement in avoidance in major depressive disorder: A 10-month prospective study of depressive symptoms and personality traits.PCN reports : psychiatry and clinical neurosciences · 2026Article
- Association between miR-182 rs76481776 Polymorphism and Antidepressant Treatment Response in Patients with Depression.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2026Article
- 7-Tesla ultra-high field MRI of the parahippocampal cortex reveals evidence of common neurobiological mechanisms of major depressive disorder and neurotic personality traits.Translational psychiatry · 2025Article
- Predictors of Changes in Depressive Symptoms with Major Depressive Disorder - A Naturalistic 6-month Follow-up Study.Neuropsychiatric disease and treatment · 2025Article
- Association of personality traits with rumination improvement following cognitive behavioral therapy in major depression: an observational study.Frontiers in psychiatry · 2025Article
- Intraindividual phenotyping of depression in high-risk youth: An application of a multilevel hidden Markov model.Development and psychopathology · 2023Article
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12 authors.
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Abstract
Purpose: Major depression is a heterogeneous disorder. Therefore, careful evaluation and comprehensive assessment are crucial elements for achieving remission. Personality traits influence prognosis and treatment outcomes, but there is not enough evidence on the association between personality traits and sustained remission (SR). Hence, the present study aimed to evaluate the relationship between personality traits and SR among patients with major depression. Patients and Methods: The 12-month prospective study evaluated 77 patients diagnosed with major depressive disorder. All patients underwent a comprehensive assessment, including the Temperament and Personality Questionnaire (T&P) at baseline, and depression severity was measured at baseline as well as six and 12 months. SR was defined as remission (the GRID-Hamilton Depression Rating Scale [GRID-HAMD Results: Patients who achieved SR had a lower T&P personal reserve and lower T&P rejection sensitivity. Further, lower scores on the T&P personal reserve trait were independently associated with higher rates of SR among patients with major depression. Patients who achieved SR had a shorter duration of the current depressive episode and milder severity of depression at baseline. Conclusion: A lower level of personal reserve predicted a higher probability of SR in the treatment of depression. Extended observations in naturalistic follow-up settings with larger sample sizes are required to better understand the personality traits affecting SR in patients with depression.
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