ArticleThe British journal of psychiatry : the journal of mental science2023
Dose-response association of handgrip strength and risk of depression: a longitudinal study of 115 601 older adults from 24 countries.
Article in The British journal of psychiatry : the journal of mental science, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical importance of simple muscular fitness tests to predict long-term health conditions: a systematic review and meta-analysis of 94 cohort studies.British journal of sports medicine · 2026Pooled it
- Handgrip strength and relationship with non-motor symptoms in Parkinson's disease.Journal of Parkinson's disease · 2026Article
- Mind, Mood, and Mobility: Rethinking Functional Disability Prevention in Older Adults on the Basis of a Longitudinal Cohort From CHARLS.Journal of the American Heart Association · 2026Article
- The role of depression in the association between handgrip strength and mild cognitive impairment among Chinese older adults.BMC geriatrics · 2026Article
- Dose-Response Association Between Handgrip Strength and All-Cause Mortality Across Different Levels of Systemic Inflammation.Journal of cachexia, sarcopenia and muscle · 2026Article
- Handgrip strength predicts incident depression in Chinese older adults: a national prospective cohort study.BMC geriatrics · 2026Article
- Empathy in Public Safety: Selection Standards, Gender Differences, and Relations with Existing Selection Predictors.Journal of functional morphology and kinesiology · 2026Article
- Trends in depression in the European population aged 50 years and older by geographic region.American journal of epidemiology · 2026Article
- Activity-function transitions and interpretable machine learning for predicting incident depressive symptoms among ACE-exposed middle-aged and older adults: a multi-cohort study.Frontiers in public health · 2026Article
- Antidepressant Effects ofFoods (Basel, Switzerland) · 2025Article
- Muscle strength and the risk of Multimorbidity in Middle-aged and older Chinese adults: A prospective cohort study.Aging clinical and experimental research · 2025Article
- Cumulative handgrip strength and trajectories of depressive symptoms in older adults: evidence from two cohort studies.BMC public health · 2025Article
- Dietary Habits and Obesity in Middle-Aged and Elderly Europeans-The Survey of Health, Ageing, and Retirement in Europe (SHARE).Nutrients · 2025Article
- In search of a characterisation of frailty: applying exploratory factor analysis to ageing preoperative patients : Cross-sectional study.Perioperative medicine (London, England) · 2025Article
- The Relationship Between Grip Strength and Cognitive Impairment: Evidence From NHANES 2011-2014.Brain and behavior · 2025Article
- Article
- Optimal dose and pattern of physical activity to prevent diagnosed depression: prospective cohort study.Psychological medicine · 2025Article
- Connecting the dots: sex, depression, and musculoskeletal health.The Journal of clinical investigation · 2024Review
- Bidirectional Associations Between Cardiometabolic Multimorbidity and Depression and Mediation of Lifestyles: A Multicohort Study.JACC. Asia · 2024Article
- Predictors of the onset of low handgrip strength in Europe: a longitudinal study of 42,183 older adults from 15 countries.Aging clinical and experimental research · 2024Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrior research has solely focused on the association between handgrip strength and risk of depression in single countries or general populations, but more knowledge is required from wider-spread cohorts and target populations.
aimsThis study aimed to investigate the association between handgrip strength and risk of depression using repeated measures in adults aged 50 years and over.
methodData on handgrip strength and risk of depression were retrieved from the Survey of Health, Ageing and Retirement in Europe (SHARE) waves 1, 2, 4, 5, 6 and 7, using a hand dynamometer (Smedley, S Dynamometer, TTM) and the EURO-D 12-item scale, respectively. Time-varying exposure and covariates were modelled using both Cox regression and restricted cubic splines.
resultsA total of 115 601 participants (mean age 64.3 years (s.d. = 9.9), 54.3% women) were followed-up for a median of 7.3 years (interquartile range: 3.9-11.8) and 792 459 person-years. During this period, 30 208 (26.1%) participants experienced a risk of depression. When modelled as a continuous variable, we observed an inverse significant association for each kg increase of handgrip strength and depression up to 40 kg in men and up to 27 kg in women.
conclusionsBeing physically strong may serve as a preventive factor for depression in older adults, but this is limited up to a maximum specific threshold for men and women.
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