Evidence map›Paper›PMID 36464928›Full record

ArticleJournal of traumatic stress2023

Posttraumatic stress disorder, diurnal cortisol, and ambulatory blood pressure in early and late pregnancy.

Margaret H Bublitz, Yael Nillni, Nicole R Nugent, Laura Sanapo, Naya Habr, Ghada Bourjeily

Open access · greenAbstract read
In one paragraph

Article in Journal of traumatic stress, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Margaret H BublitzDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.ORCID 0000-0001-8765-7846
Yael NillniDepartment of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, Massachusetts, USA.
Nicole R NugentDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.ORCID 0000-0001-8756-5618
Laura SanapoDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Naya HabrWomen's Medicine Collaborative, The Miriam Hospital, Providence, Rhode Island, USA.
Ghada BourjeilyDepartment of Medicine, Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.
Brown University · USBoston University · USMiriam Hospital · US

Funding

Placental role in mediating adverse outcomes in obstructive sleep apneaR01HD078515 · NICHD · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2014 to 2018
$2.7M
Predictors of de novo development of obstructive sleep apnea in pregnancyR01HL130702 · NHLBI · MIRIAM HOSPITAL · PI BOURJEILY, GHADA · 2016 to 2020
$2.6M
PTSD-Related Neurobiological Mediators of Negative Pregnancy OutcomesK23HD087428 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NILLNI, YAEL I · 2017 to 2020
$616k
NHLBI NIH HHS R01 HL130702NICHD NIH HHS K23 HD087428NICHD NIH HHS R01 HD078515
6 · The paper itself

Abstract

Posttraumatic stress disorder (PTSD) affects 1 in 20 reproductive-aged women and is associated with cardiovascular disease morbidity and mortality. The pathophysiology linking PTSD to cardiovascular disease in nonpregnant adults is proposed to include hypothalamic and autonomic dysregulation; however, the pathways explaining this association in pregnancy are unclear. We examined diurnal cortisol and ambulatory blood pressure (BP) among 254 pregnant women at approximately 12 and 32 gestational weeks. Participants were, on average, 31 years old (SD = 5), 24.4% reported their ethnicity as Hispanic, and 62.2% reported their race as White. PTSD symptoms were measured using the PTSD Checklist for DSM-5 (PCL-5). Hierarchical linear regression analyses were performed to examine associations pregnancy between PTSD and cortisol at awakening, 30 min after awakening, and bedtime in early and late pregnancy, as well as associations between PTSD symptoms and daytime and nighttime systolic (SBP) and diastolic BP (DBP) and BP variability. Logistic regression analyses were conducted to test associations between PTSD symptoms and BP dipping. The results showed a positive association between PTSD symptoms and nighttime BP and BP variability at 32 gestational weeks, ∆R

Indexed as

Cardiovascular DiseasesStress Disorders, Post-TraumaticAdultBlood PressureBlood Pressure Monitoring, AmbulatoryCircadian RhythmFemaleHumansHydrocortisonePregnancyHydrocortisone

Identifiers

PMID36464928
PMCPMC11079916
OpenAlexW4310676554

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.