Evidence map›Paper›PMID 36463930›Full record

ArticleDiabetes care2023

Vegetable, but Not Potato, Intake Is Associated With a Lower Risk of Type 2 Diabetes in the Danish Diet, Cancer and Health Cohort.

Pratik Pokharel, Cecilie Kyrø, Anja Olsen, Anne Tjønneland, Kevin Murray, Lauren C Blekkenhorst, Catherine P Bondonno, Jonathan M Hodgson, Nicola P Bondonno

Open access · bronzeAbstract read
In one paragraph

Article in Diabetes care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Perspective: Potatoes, Quality Carbohydrates, and Dietary Patterns.Advances in nutrition (Bethesda, Md.) · 2024
    Article
  10. Article
  11. Vitamin K1 Intake and Incident Diabetes in the Danish Diet, Cancer, and Health Study.The Journal of clinical endocrinology and metabolism · 2023
    Article
4 · The record

Corrections and comments

  • Commented on by
    2023
5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Pratik PokharelDanish Cancer Society Research Center, Copenhagen, Denmark.ORCID 0000-0001-5815-5927
Cecilie KyrøDanish Cancer Society Research Center, Copenhagen, Denmark.
Anja OlsenDanish Cancer Society Research Center, Copenhagen, Denmark.
Anne TjønnelandDanish Cancer Society Research Center, Copenhagen, Denmark.
Kevin MurraySchool of Population and Global Health, University of Western Australia, Perth, Australia.
Lauren C BlekkenhorstNutrition & Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Australia.
Catherine P BondonnoNutrition & Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Australia.
Jonathan M HodgsonNutrition & Health Innovation Research Institute, School of Medical and Health Sciences, Edith Cowan University, Perth, Australia.
Nicola P BondonnoDanish Cancer Society Research Center, Copenhagen, Denmark.ORCID 0000-0001-5905-444X
Edith Cowan University · AUAarhus University · DKDanish Cancer Society · DKThe University of Western Australia · AUUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the relationship between intake of vegetables/potatoes and incident type 2 diabetes (T2D) and explore whether the relationship between vegetable intake and incident T2D is mediated by baseline BMI. RESEARCH DESIGN AND

methodsCross-sectional associations between exposure (baseline intake of total vegetables, vegetable subgroups, and potatoes) and baseline BMI were assessed by multivariable-adjusted linear regression models. Associations between exposure and incident T2D were examined by multivariable-adjusted Cox proportional hazards models. Mediation by BMI was quantified through exploration of natural direct and indirect effects.

resultsAmong 54,793 participants in the Danish Diet, Cancer and Health cohort, 7,695 cases of T2D were recorded during a median follow-up of 16.3 years. Participants in the highest total vegetable intake quintile (median 319 g/day) had a 0.35 kg/m2 (95% CI -0.46, -0.24) lower BMI and a 21% (95% CI 16, 26%) lower risk of incident T2D after multivariable adjustment compared with those in the lowest quintile (median 67 g/day). Baseline BMI mediated ∼21% of the association between vegetable intake and incident T2D. Participants in the highest compared with the lowest (median 256 vs. 52 g/day) potato intake quintile had a 9% (95% CI 2, 16%) higher risk of T2D after multivariable adjustment, with no association found after accounting for underlying dietary pattern. Of the vegetable subclasses, higher intake of green leafy and cruciferous vegetables was associated with a statistically significantly lower risk of T2D.

conclusionsThe findings provide evidence that a higher vegetable, but not potato, intake might help mitigate T2D risk, partly by reducing BMI.

Indexed as

Diabetes Mellitus, Type 2NeoplasmsSolanum tuberosumCross-Sectional StudiesDenmarkDietHumansProspective StudiesRisk FactorsVegetables

Identifiers

PMID36463930
PMCPMC9887631
OpenAlexW4310707519

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.