Evidence map›Paper›PMID 36463649›Full record

ArticleJournal of chromatography. A2023

A rapid and systematic approach for the optimization of radio thin-layer chromatography resolution.

Travis S Laferriere-Holloway, Alejandra Rios, Yingqing Lu, Chelsea C Okoro, R Michael van Dam

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of chromatography. A, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Travis S Laferriere-HollowayDepartment of Molecular & Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA; Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA, USA. Electronic address: tholloway@mednet.ucla.edu.
Alejandra RiosPhysics and Biology in Medicine Interdepartmental Graduate Program, UCLA, Los Angeles, CA, USA; Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA, USA.
Yingqing LuPhysics and Biology in Medicine Interdepartmental Graduate Program, UCLA, Los Angeles, CA, USA; Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA, USA.
Chelsea C OkoroInstitute for Society and Genetics, UCLA, Los Angeles, CA, USA; Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA, USA.
R Michael van DamDepartment of Molecular & Medical Pharmacology, David Geffen School of Medicine, University of California Los Angeles (UCLA), Los Angeles, CA, USA; Physics and Biology in Medicine Interdepartmental Graduate Program, UCLA, Los Angeles, CA, USA; Crump Institute for Molecular Imaging, UCLA, Los Angeles, CA, USA. Electronic address: mvandam@mednet.ucla.edu.

Funding

MARC U*STAR Program at the University of California, Los AngelesT34GM008563 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MCEVOY, MEGAN M, POE, GINA R · 1996 to 2023
$9.7M
Research Training in Biomedical PhysicsT32EB002101 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Michael F McNitt-Gray · 2003 to 2026
$5.3M
Accelerating the discovery and development of neurotracers via high-throughput radiochemistryR01EB032264 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHATZIIOANNOU, ARION XENOFON, VAN DAM, ROBERT MICHAEL · 2022 to 2025
$2.7M
Optimization and validation of integrated microscale technologies for low-cost, automated production of PET molecular imaging tracers for cancer researchR33CA240201 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DAM, ROBERT MICHAEL · 2019 to 2021
$1.1M
High-throughput radiochemistry platform for accelerated discovery and development of novel PET imaging agents for cancerR21CA212718 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DAM, ROBERT MICHAEL · 2017 to 2018
$616k
Novel microscale purification methods for complete microfluidic production of high molar activity PET radiotracersR21EB024243 · NIBIB · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DAM, ROBERT MICHAEL · 2019 to 2020
$429k
Radio-UPLC-MS for high-throughput analysis of short-lived radiolabeled compoundsS10OD026942 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DAM, ROBERT MICHAEL · 2019 to 2019
$199k
NCI NIH HHS R21 CA212718NCI NIH HHS R33 CA240201NIBIB NIH HHS R01 EB032264NIBIB NIH HHS R21 EB024243NIBIB NIH HHS T32 EB002101NIGMS NIH HHS T34 GM008563NIH HHS S10 OD026942
6 · The paper itself

Abstract

Radiopharmaceutical analysis is limited by conventional methods. Radio-HPLC may be inaccurate for some compounds (e.g.,

Indexed as

BenzamidesRadiopharmaceuticalsChromatography, High Pressure LiquidChromatography, Thin LayerSolventsBenzamidesfallyprideRadiopharmaceuticalsSolventshigh-resolutionPRISMA optimizationRadiochemistryradiopharmaceuticalsradio-TLC

Identifiers

PMID36463649
PMCPMC9894532

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.