Evidence map›Paper›PMID 36463365›Full record

ArticleMedical microbiology and immunology2023

Acinetobacter baumannii reinforces the pathogenesis by promoting IL-17 production in a mouse pneumonia model.

Yangyang Zhou, Chuanying Xiang, Ning Wang, Xiaomin Zhang, Yu Xie, Hong Yang, Gang Guo, Kaiyun Liu, Yan Li, Yun Shi

Abstract read
PubMed Publisher
In one paragraph

Article in Medical microbiology and immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. From screening to treatment:Microbiology spectrum · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. The IL-17 family in diseases: from bench to bedside.Signal transduction and targeted therapy · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Yangyang Zhou *West China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Chuanying Xiang *West China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Ning WangWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Xiaomin ZhangWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Yu XieWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Hong YangWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Gang GuoWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Kaiyun LiuWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China.
Yan LiWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. lliyan@hotmail.com.
Yun ShiWest China Biopharmaceutical Research Institute, West China Hospital, Sichuan University, Chengdu, 610041, Sichuan, China. shiyun@wchscu.cn.ORCID http://orcid.org/0000-0003-1925-4337
Sichuan University · CN

Funding

National Natural Science Foundation of China 81971561West China Hospital, Sichuan University 1·3·5 project for disciplines of excellence (No. ZYXY21004)
6 · The paper itself

Abstract

Interleukin-17 (IL-17) is involved in host defense against bacterial infection. Little is known about the role of IL-17 in A. baumannii-infected pneumonia. Our objective was to investigate the role of IL-17 in pulmonary A. baumannii infection in a mouse model. We infected C57BL/6 mice intra-tracheally (i.t.) with A. baumannii to establish pneumonia model and found A. baumannii infection elevated IL-17 expression in lungs. IL-17-deficient (Il17

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsPneumoniaAnimalsDisease Models, AnimalInterleukin-17LungMiceMice, Inbred C57BLNeutrophilsIl17a protein, mouseInterleukin-17A. baumanniiIL-17NeutrophilPhagocytosis

Identifiers

PMID36463365
OpenAlexW4310668410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.