ArticleJournal of translational medicine2022
Survival outcomes following treatment delays among patients with early-stage female cancers: a nationwide study.
Article in Journal of translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Psychological Factors Related to Treatment Outcomes in Head and Neck Cancer.Advances in therapy · 2024Pooled it
- Care delivery among patients with early-onset versus average-onset cholangiocarcinoma: a nationwide retrospective analysis.ESMO gastrointestinal oncology · 2026Article
- Trends, Disparities, and Outcomes in Time to Treatment Initiation in Patients With Early-Onset Colorectal Cancer.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Influence of Diagnostic and Treatment Delays on Survival Outcomes in Patients With Locally Advanced Rectal Cancer: A Multi-Center Retrospective Cohort Study.Cancer medicine · 2026Article
- Exploring Transitions in Care Among Patients With Head and Neck Cancer: A Scoping Review.Head & neck · 2026Article
- Re-Evaluating Access in Healthcare: Focus on Quality of Care.Public health challenges · 2025Review
- Delay to timely treatment in locally advanced cervical cancer: insurance inequities in access to gynecologic oncology.American journal of obstetrics and gynecology · 2025Article
- Article
- Time-to-Treatment Initiation and Its Effect on All-Cause Mortality: Insights From the Surveillance, Epidemiology, and End Results Database.World journal of oncology · 2025Article
- Effect of delayed treatment on survival of patients with head and neck squamous cell cancer.Scientific reports · 2025Article
- Socioeconomic status and delayed breast cancer care in Southeast Texas: a retrospective cohort study.Proceedings (Baylor University. Medical Center) · 2025Article
- Changes in female cancer diagnostic billing rates over the COVID-19 period in the Ontario Health Insurance Plan.Therapeutic advances in medical oncology · 2025Article
- Opportunities and challenges encountered in managing cervical cancer during the coronavirus disease 2019 pandemic.Infectious agents and cancer · 2024Review
- Trends in gynaecologic cancer mortality and the impact of the COVID-19 pandemic in the United States.Infectious agents and cancer · 2024Article
- Impact of Treatment Delay on the Prognosis of Patients with Ovarian Cancer: A Population-based Study Using the Surveillance, Epidemiology, and End Results Database.Journal of Cancer · 2024Article
- Impact of treatment delays on future survival outcomes in non-surgical patients with esophageal cancer in Shandong Province, China.Frontiers in oncology · 2024Article
- Research Hotspots and Frontiers of Patient Delay: A Bibliometric Analysis from 2000 to 2023.Journal of multidisciplinary healthcare · 2024Article
- Association between surgery treatment delays and survival outcomes in patients with esophageal cancer in Hebei, China.Frontiers in oncology · 2024Article
- Article
- Treatment delays for cancer patients in Sub-Saharan Africa: South Africa as a microcosm.Ecancermedicalscience · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe coronavirus disease 2019 (COVID-19) severely hindered the timely receipt of health care for patients with cancer, especially female patients. Depression and anxiety were more pronounced in female patients than their male counterparts with cancer during treatment wait-time intervals. Herein, investigating the impact of treatment delays on the survival outcomes of female patients with early-stage cancers can enhance the rational and precise clinical decisions of physicians.
methodsWe analyzed five types of cancers in women from the Surveillance, Epidemiology, and End Results (SEER) program between Jan 2010 and Dec 2015. Univariate and multivariate Cox regression analyses were used to determine the impacts of treatment delays on the overall survival (OS) and cancer-specific survival (CSS) of the patients.
resultsA total of 241,661 females with early-stage cancer were analyzed (12,617 cases of non-small cell lung cancer (NSCLC), 166,051 cases of infiltrating breast cancer, 31,096 cases of differentiated thyroid cancer, 23,550 cases of colorectal cancer, and 8347 cases of cervical cancer). Worse OS rates were observed in patients with treatment delays ≥ 3 months in stage I NSCLC (
conclusionAfter adjusting for confounders, the prolonged time from diagnosis to the initiation of treatment (< 6 months) showed limited negative effects on the survival of most of the patients with early-stage female cancers. Whether our findings serve as evidence supporting the treatment deferral decisions of clinicians for patients with different cancers in resource-limited situations needs further validation.
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