Evidence map›Paper›PMID 36462146›Full record

ArticleEndocrine2023

Clinical evaluation of malignancy diagnosis of rare thyroid carcinomas by an artificial intelligent automatic diagnosis system.

Yuan Wang, Lei Xu, Wenliang Lu, Xiangkai Kong, Kaiyuan Shi, Liping Wang, Dexing Kong

Abstract read
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In one paragraph

Article in Endocrine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Yuan Wang *School of Mathematical Sciences, Zhejiang University, Hangzhou, China.
Lei Xu *Zhejiang Qiushi Institute for Mathematical Medicine, Hangzhou, China.
Wenliang LuSchool of Mathematical Sciences, Zhejiang University, Hangzhou, China.
Xiangkai KongDepartment of Ultrasonography, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Hangzhou, China.
Kaiyuan ShiDepartment of Ultrasonography, The Cancer Hospital of the University of Chinese Academy of Sciences (Zhejiang Cancer Hospital), Institute of Basic Medicine and Cancer, Chinese Academy of Sciences, Hangzhou, China.
Liping WangZhejiang Society for Mathematical Medicine, Hangzhou, China. wanglp@zjcc.org.cn.ORCID 0000-0003-2654-2337
Dexing KongSchool of Mathematical Sciences, Zhejiang University, Hangzhou, China. dxkong@zju.edu.cn.
Zhejiang Cancer Hospital · CNZhejiang Lab · CNZhejiang University · CN

Funding

National Natural Science Foundation of China No. 12090020Zhejiang Provincial Natural Science Foundation of China No. LY20H180001
6 · The paper itself

Abstract

purposeTo evaluate the application value of a generally trained artificial intelligence (AI) automatic diagnosis system in the malignancy diagnosis of rare thyroid carcinomas, such as follicular thyroid carcinoma, medullary thyroid carcinoma, primary thyroid lymphoma and anaplastic thyroid carcinoma and compare the diagnostic performance with radiologists of different experience levels.

methodsWe retrospectively studied 342 patients with 378 thyroid nodules that included 196 rare malignant nodules by using postoperative pathology as the gold standard, and compared the diagnostic performances of three radiologists (one junior, one mid-level, one senior) and that of AI automatic diagnosis system.

resultsThe accuracy of the AI system in malignancy diagnosis was 0.825, which was significantly higher than that of all three radiologists and higher than the best radiologist in this study by a margin of 0.097 with P-value of 2.252 × 10

conclusionsThe generally trained AI automatic diagnosis system showed high accuracy in the differential diagnosis of begin nodules and rare malignancy nodules. It may assist radiologists for screening of rare malignancy nodules that even senior radiologists are not acquainted with.

Indexed as

Thyroid NeoplasmsThyroid NoduleArtificial IntelligenceHumansRetrospective StudiesROC CurveUltrasonographyAI automatic diagnosis systemRadiologistsRare thyroid carcinomasUltrasonic

Identifiers

PMID36462146
OpenAlexW4310643059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.