Evidence map›Paper›PMID 36462137›Full record

ArticleResearch on child and adolescent psychopathology2023

A Multi-Cohort Examination of the Independent Contributions of Maternal Childhood Adversity and Pregnancy Stressors to the Prediction of Children's Anxiety and Depression.

Amanda Noroña-Zhou, Michael Coccia, Alexis Sullivan, Thomas G O'Connor, Brent R Collett, Karen Derefinko, Lynette M Renner, Christine T Loftus, Danielle Roubinov, Kecia N Carroll and 7 more

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In one paragraph

Article in Research on child and adolescent psychopathology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Observational
  4. A Call to Integrate Measures of Environmental Context into Research on Maternal Brain Health.International journal of environmental research and public health · 2025
    Review
  5. Article
  6. Article
  7. Review
  8. Maternal stressful life events during pregnancy and childhood asthma and wheeze.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Amanda Noroña-ZhouDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), San Francisco, CA, USA. amanda.norona-zhou@ucsf.edu.
Michael CocciaCenter for Health and Community, UCSF, San Francisco, CA, USA.
Alexis SullivanDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), San Francisco, CA, USA.
Thomas G O'ConnorDepartments of Psychiatry, Psychology, Neuroscience, Department of Obstetrics & Gynecology, University of Rochester, Rochester, NY, USA.
Brent R CollettDepartment of Psychiatry & Behavioral Sciences, University of Washington, Seattle Children's Research Institute, Seattle, WA, USA.
Karen DerefinkoDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Lynette M RennerSchool of Social Work, University of Minnesota, Minneapolis, MN, USA.
Christine T LoftusDepartment of Occupational and Environmental Health Sciences, University of Washington, Seattle, WA, USA.
Danielle RoubinovDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), San Francisco, CA, USA.
Kecia N CarrollDepartments of Environmental Medicine and Public Health and Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Ruby H N NguyenDivision of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA.
Catherine J KarrDepartment of Occupational and Environmental Health Sciences, Department of Pediatrics, University of Washington, Seattle, WA, USA.
Sheela SathyanarayanaDepartment of Psychiatry & Behavioral Sciences, University of Washington, Seattle Children's Research Institute, Seattle, WA, USA.
Emily S BarrettDepartment of Biostatistics and Epidemiology, Rutgers School of Public Health; Environmental and Occupational Health Sciences Institute, Rutgers University, New Brunswick, NJ, USA.
W Alex MasonDepartment of Preventive Medicine, University of Tennessee Health Science Center, Memphis, TN, USA.
Kaja Z LeWinnDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), San Francisco, CA, USA.
Nicole R BushDepartment of Psychiatry and Behavioral Sciences, Weill Institute for Neurosciences, University of California, San Francisco (UCSF), San Francisco, CA, USA.

Funding

Transform Dissemination and Implementation Science in CTSA ProgramsUL1TR002319 · NCATS · UNIVERSITY OF WASHINGTON · PI John K. Amory · 2017 to 2026
$100.0M
Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI BRIAN T BUCKLEY · 1988 to 2026
$47.4M
XENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Nicole Ann Errett · 1995 to 2026
$42.5M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUH3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2018 to 2022
$37.3M
TIDES III: Endocrine Disruption, Hormones, and Sex Differences in Adolescent Airway HealthR01ES025169 · NIEHS · SEATTLE CHILDREN'S HOSPITAL · PI Sheela Sathyanarayana · 2015 to 2026
$9.5M
Prenatal and Early Childhood Pathways To Health:  An Integrated Model of Chemical and Social Exposures, Biological Mechanisms, and Sex-Specific Effects on Neurodevelopment and Respiratory OutcomesUG3OD023271 · OD · UNIVERSITY OF WASHINGTON · PI BUSH, NICOLE RENEE, KARR, CATHERINE J · 2016 to 2017
$5.1M
The Infant Development and the Environmental Study (TIDES)R01ES016863 · NIEHS · UNIVERSITY OF ROCHESTER · PI SWAN, SHANNA H · 2009 to 2014
$4.0M
Maternal Traumatic Stress, Oxidative Stress, Antioxidant Exposures, and Child Asthma and Lung FunctionR01HL132338 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CARROLL, KECIA NICOLE, WRIGHT, ROSALIND J · 2017 to 2021
$3.8M
Pregnancy Folate Status & Early Childhood Respiratory & Atopic Disease OutcomesR01HL109977 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CARROLL, KECIA NICOLE · 2011 to 2015
$3.4M
NCATS NIH HHS UL1 TR002319NCATS NIH HHS UL1TR002319NHLBI NIH HHS R01 HL109977NHLBI NIH HHS R01 HL132338NIEHS NIH HHS 1R01ES25169NIEHS NIH HHS P30 ES005022NIEHS NIH HHS P30ES005022NIEHS NIH HHS P30 ES007033NIEHS NIH HHS R01 ES016863NIEHS NIH HHS R01 ES025169NIH HHS UG3 OD023271NIH HHS UH3 OD023271
6 · The paper itself

Abstract

Women's social experiences can have long-term implications for their offspring's health, but little is known about the potential independent contributions of multiple periods of stress exposures over time. This study examined associations of maternal exposure to adversity in childhood and pregnancy with children's anxiety and depression symptoms in a large, sociodemographically diverse sample. Participants were 1389 mother-child dyads (child age M = 8.83 years; SD = 0.66; 42% Black, 42% White; 6% Hispanic) in the ECHO-PATHWAYS Consortium's three U.S. pregnancy cohorts. Women reported their exposure to childhood traumatic events (CTE) and pregnancy stressful life events (PSLE). Children self-reported on their symptoms of anxiety and depression at age 8-9 years. Regression analyses estimated associations between maternal stressors and children's internalizing problems, adjusting for confounders, and examined child sex as a modifier. Exploratory interaction analyses examined whether geospatially-linked postnatal neighborhood quality buffered effects. In adjusted models, PSLE counts positively predicted levels of children's anxiety and depression symptoms ([ß

Indexed as

Adverse Childhood ExperiencesDepressionAnxietyAnxiety DisordersChildFamilyFemaleHumansMalePregnancyChild anxietyChild depressionChildhood traumaIntergenerational transmissionPregnancy stress

Identifiers

PMID36462137
PMCPMC10017630

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.