Evidence map›Paper›PMID 36462118›Full record

ReviewJournal of materials science. Materials in medicine2022

Polymeric Nanofibers for Drug Delivery Applications: A Recent Review.

Xiaoge Duan, Hai-Lan Chen, Chunxian Guo

Abstract readReview
In one paragraph

Review in Journal of materials science. Materials in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
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  8. Article
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  11. Living Nanofiber-Enabled Cardiac Patches for Myocardial Injury.JACC. Basic to translational science · 2025
    Review
  12. Review
  13. Article
  14. Review
  15. Synergistic Dual Antibacterial Activity of Magnetite Hydrogels Doped with Silver.Langmuir : the ACS journal of surfaces and colloids · 2024
    Article
  16. Review
  17. Review
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaoge DuanCollege of Animal Science and Technology, Guangxi University, Nanning, 530005, China.
Hai-Lan ChenCollege of Animal Science and Technology, Guangxi University, Nanning, 530005, China. hlchen319@163.com.ORCID http://orcid.org/0000-0002-1733-5267
Chunxian GuoSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, China. cxguo@usts.edu.cn.

Funding

National Key Research and Development Program of China 2021YFA0910400National Natural Science Foundation of China 21763004
6 · The paper itself

Abstract

With the rapid development of biomaterials and biotechnologies, various functional materials-based drug delivery systems (DDS) are developed to overcome the limitations of traditional drug release formulations, such as uncontrollable drug concentration in target organs/tissues and unavoidable adverse reactions. Polymer nanofibers exhibit promising characteristics including easy preparation, adjustable features of wettability and elasticity, tailored surface and interface properties, and surface-to-volume ratio, and are used to develop new DDS. Different kinds of drugs can be incorporated into the polymer nanofibers. Additionally, their release kinetics can be modulated via the preparation components, component proportions, and preparation processes, enabling their applications in several fields. A timely and comprehensive summary of polymeric nanofibers for DDS is thus highly needed. This review first describes the common methods for polymer nanofiber fabrication, followed by introducing controlled techniques for drug loading into and release from polymer nanofibers. Thus, the applications of polymer nanofibers in drug delivery were summarized, particularly focusing on the relation between the physiochemical properties of polymeric nanofibers and their DDS performance. It is ended by listing future perspectives. Graphical abstract.

Indexed as

NanofibersBiocompatible MaterialsDrug Delivery SystemsPolymersWettabilityBiocompatible MaterialsPolymers

Identifiers

PMID36462118
PMCPMC9719450

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.