Evidence map›Paper›PMID 36462108›Full record

ArticleScience China. Life sciences2023

Disease resistance conferred by components of essential chrysanthemum oil and the epigenetic regulation of OsTPS1.

Chuansong Zhan, Long Lei, Hao Guo, Shen Zhou, Congping Xu, Zixin Liu, Zichen Wu, Yuan Deng, Yuanyuan Miao, Yu Han and 12 more

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Science China. Life sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. EngineeredJournal of fungi (Basel, Switzerland) · 2026
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  2. Analysis of biosynthetic genes of phenolamides inFrontiers in plant science · 2026
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  3. Article
  4. Article
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  7. Review
  8. Rice Responses to Abiotic Stress: Key Proteins and Molecular Mechanisms.International journal of molecular sciences · 2025
    Review
  9. Article
  10. Article
  11. Bactericidal bissulfone BScience China. Life sciences · 2024
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 3 institutions in 2 countries.

Chuansong Zhan *College of Tropical Crops, Hainan University, Haikou, 570228, China.
Long Lei *College of Tropical Crops, Hainan University, Haikou, 570228, China.
Hao Guo *College of Tropical Crops, Hainan University, Haikou, 570228, China.
Shen Zhou *College of Tropical Crops, Hainan University, Haikou, 570228, China.
Congping Xu *College of Tropical Crops, Hainan University, Haikou, 570228, China.
Zixin LiuNational Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan, 430070, China.
Zichen WuCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Yuan DengCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Yuanyuan MiaoCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Yu HanCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Meng ZhangNational Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan, 430070, China.
Hua LiCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Sishu HuangCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Chenkun YangNational Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan, 430070, China.
Feng ZhangNational Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan, 430070, China.
Yufei LiNational Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan, 430070, China.
Ling LiuCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Xianqing LiuCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Hafiz Muhammad Khalid AbbasCollege of Tropical Crops, Hainan University, Haikou, 570228, China.
Alisdair R FernieMax Planck Institute of Molecular Plant Physiology, Am Mühlenberg 1, 14476, Potsdam-Golm, Germany.
Meng YuanNational Key Laboratory of Crop Genetic Improvement and National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University, Wuhan, 430070, China. myuan@mail.hzau.edu.cn.
Jie LuoCollege of Tropical Crops, Hainan University, Haikou, 570228, China. jie.luo@hainanu.edu.cn.
Hainan University · CNHuazhong Agricultural University · CNMax Planck Institute of Molecular Plant Physiology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sesquiterpene alpha-bisabolol is the predominant active ingredient in essential oils that are highly valued in the cosmetics industry due to its wound healing, anti-inflammatory, and skin-soothing properties. Alpha-bisabolol was thought to be restricted to Compositae plants. Here we reveal that alpha-bisabolol is also synthesized in rice, a non-Compositae plant, where it acts as a novel sesquiterpene phytoalexin. Overexpressing the gene responsible for the biosynthesis of alpha-bisabolol, OsTPS1, conferred bacterial blight resistance in rice. Phylogenomic analyses revealed that alpha-bisabolol-synthesizing enzymes in rice and Compositae evolved independently. Further experiments demonstrated that the natural variation in the disease resistance level was associated with differential transcription of OsTPS1 due to polymorphisms in its promoter. We demonstrated that OsTPS1 was regulated at the epigenetic level by JMJ705 through the methyl jasmonate pathway. These data reveal the cross-family accumulation and regulatory mechanisms of alpha-bisabolol production.

Indexed as

ChrysanthemumOils, VolatileSesquiterpenesDisease ResistanceEpigenesis, GeneticMonocyclic SesquiterpenesbisabololMonocyclic SesquiterpenesOils, VolatileSesquiterpenesalpha-bisabololepigenetic regulationnatural variation

Identifiers

PMID36462108
OpenAlexW4310640227

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.