Evidence map›Paper›PMID 36461762›Full record

ArticleActa radiologica (Stockholm, Sweden : 1987)2023

Feasibility of monitoring the resolution of acute pulmonary embolism with non-contrast-enhanced magnetic resonance imaging at one day, one week, one, three, and six months.

Koshiar Medson, Eli Westerlund, Roberto Vargas Paris, Alexander Fyrdahl, Nina Vidovic, Sven Nyren, Peter Lindholm

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Acta radiologica (Stockholm, Sweden : 1987), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Koshiar MedsonDepartment of Physiology and Pharmacology, 27106Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-9209-7801
Eli WesterlundDepartment of Clinical Sciences, 27106Karolinska Institutet, Stockholm, Sweden.
Roberto Vargas ParisDepartment of Physiology and Pharmacology, 27106Karolinska Institutet, Stockholm, Sweden.
Alexander FyrdahlDepartment of Molecular Medicine and Surgery, 27106Karolinska Institutet, Stockholm, Sweden.
Nina VidovicDepartment of Radiology, Mälarsjukhuset, Eskilstuna, Sweden.
Sven NyrenDepartment of Imaging and Physiology, Karolinska University Hospital, Stockholm, Sweden.
Peter LindholmDepartment of Physiology and Pharmacology, 27106Karolinska Institutet, Stockholm, Sweden.
Karolinska University Hospital · SEKarolinska Institutet · SEDanderyds sjukhus · SEUppsala University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPulmonary embolism (PE) is a common cause of death with an incidence of approximately 1-2 cases per 1000 inhabitants in Europe and the United States. Treatment for PE is the administration of anticoagulants for at least three months. PURPOSE: To assess the feasibility of following the resolution rate of PE over time using repeated imaging with a non-contrast-enhanced magnetic resonance imaging (MRI) protocol. MATERIAL AND

methodsPatients (n = 18) diagnosed with acute PE via computed tomography pulmonary angiography (CTPA) underwent non-contrast-enhanced MRI at two tertiary hospitals. The first MRI was performed within 36 h of CTPA, with follow-up at one week, one, three, and six months. The MRI sequence used was a non-contrast-enhanced standard two-dimensional steady-state free precession under free-breathing and without respiratory or cardiac gating. All MRI scans were then compared to the initial CTPA. The emboli were assessed visually for location and size, and clot burden was calculated using the Qanadli score.

resultsMRI revealed complete resolution in seven cases at one week, in five cases at one month, and in three cases at three months. The most significant resolution of emboli occurred within the first few weeks, with only 10% of the diagnosed emboli persisting at the one-month examination.

conclusionThe use of MRI imparts the ability to visualize PE without radiation and thus allows multiple examinations to be made, for example in studies investigating the resolution of PE or the evaluation of drug effect in clinical trials.

Indexed as

Pulmonary EmbolismEuropeFeasibility StudiesHumansMagnetic Resonance Imagingcomputed tomography pulmonary angiographymagnetic resonance imagingpulmonary embolismsteady-state free precessionunenhanced magnetic resonance imagingVenous thromboembolism

Identifiers

PMID36461762
PMCPMC10084520
OpenAlexW4296231001

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.