Evidence map›Paper›PMID 36460991›Full record

ArticleBMC public health2022

Game-based health education to improve ART adherence of newly diagnosed young people with HIV: protocol for a stepped-wedge design randomized controlled trial.

Min Tian, Yu Zheng, Longsheng Xie, Wei Wei, Xingli Yu, Yanhua Chen, Jian Tang

Open access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Min TianDepartment of Orthopedics, The Affiliated Hospital of Southwest Medical University, 25 Taiping Street, Luzhou, China.
Yu ZhengDepartment of Rheumatology and Immunology, The Affiliated Hospital of Southwest Medical University, 25 Taiping Street, Luzhou, China.
Longsheng XieDepartment of Nephrology, Affiliated Hospital of Southwest Medical University, 25 Taiping Street, Luzhou, China.
Wei WeiSchool of Nursing, Southwest Medical University, 1 Xianglin Road, Luzhou, China.
Xingli YuDepartment of Operating Room, The Affiliated Hospital of Southwest Medical University, 25 Taiping Street, Luzhou, China.
Yanhua Chen *Department of Nursing, The Affiliated Hospital of Southwest Medical University, 25 Taiping Street, Luzhou, China. chen_yanhua25@163.com.
Jian Tang *Department of Operating Room, The Affiliated Hospital of Southwest Medical University, 25 Taiping Street, Luzhou, China. tangjian034@swmu.edu.cn.ORCID 0000-0003-2262-9419
Affiliated Hospital of Southwest Medical University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntiretroviral therapy (ART) is one of the most effective ways for HIV-infected to treat AIDS. However, it is difficult to start ART among young people those newly diagnosed HIV-infection in China, and their adherence to ART is poor. We have designed an AIDS educational game called AIDS Fighter · Health Defense, which could improve the AIDS-related knowledge and has the potential to improve AIDS prevention ability of young students. In this study, AIDS Fighter · Health Defense will be used with newly diagnosed young people with HIV to evaluate the education effect of the game in improving ART adherence.

designA stepped-wedge design randomized controlled trial will be conducted to confirm the education effect of AIDS Fighter · Health Defense on improving ART adherence of newly diagnosed young people with HIV, and to verify when to start game-based health education could be more effective for newly diagnosed young people with HIV.

methodsParticipants will receive AIDS education from health workers and start ART when diagnosed with HIV and assigned into four groups randomly. The first step group to the fourth step group will receive AIDS Fighter · Health Defense in turn at the star of ART, one week, one month and three months after the start of ART. The primary outcomes are medication adherence, CD4( +) T cell count, and HIV viral load. The secondary outcomes are ART-related knowledge, ART-related skills, psychological resilience, and self-discrimination. Assessments will be completed before the intervention and one week, first month, and third month of the intervention, and then a one-year follow-up evaluation will be conducted after the intervention. DISCUSSION: AIDS Fighter · Health Defense may be an effective approach to help newly diagnosed young people with HIV to improve ART adherence. A stepped-wedge design randomized controlled trial of this study may find the optimal time of AIDS education to improve ART adherence of newly diagnosed young people with HIV. REGISTRATION NUMBER: Chinese Clinical Trial Registry: ChiCTR2200059766, registered 11 May 2022. http://www.chictr.org.cn/showproj.aspx?proj=169420.

Indexed as

Acquired Immunodeficiency SyndromeHIV InfectionsAdolescentHealth EducationHIV TestingHumansMedication AdherenceRandomized Controlled Trials as TopicAdherenceAntiretroviral therapyGame-based educationYoung people infected with HIV

Identifiers

PMID36460991
PMCPMC9719159
OpenAlexW4310952796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.