Evidence map›Paper›PMID 36460925›Full record

ArticleEuropean radiology2023

Simultaneous multislice diffusion-weighted imaging versus standard diffusion-weighted imaging in whole-body PET/MRI.

Felipe S Furtado, Nathaniel D Mercaldo, Thomas Vahle, Thomas Benkert, William R Bradley, Lisa Ratanaprasatporn, Ravi Teja Seethamraju, Mukesh G Harisinghani, Susanna Lee, Krista Suarez-Weiss and 8 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 4 countries.

Felipe S FurtadoDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Nathaniel D MercaldoDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Thomas VahleMR Application Predevelopment, Siemens Healthcare GmbH, Allee am Roethelheimpark 2, 91052, Erlangen, Germany.
Thomas BenkertMR Application Predevelopment, Siemens Healthcare GmbH, Allee am Roethelheimpark 2, 91052, Erlangen, Germany.
William R BradleyDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Lisa RatanaprasatpornBrigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.
Ravi Teja SeethamrajuAthinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, 149 13th Street, Charlestown, MA, 02129, USA.
Mukesh G HarisinghaniDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Susanna LeeDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Krista Suarez-WeissBrigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA, 02115, USA.
Lale UmutluUniversitätsmedizin Essen, Hufelandstraße 55, 45147, Essen, Germany.
Ciprian CatanaDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA.
Kelsey L PomykalaUniversitätsmedizin Essen, Hufelandstraße 55, 45147, Essen, Germany.
Liran DomachevskySheba Medical Center, Derech Sheba 2, Ramat Gan, Israel.
Hanna BernstineTel Aviv University, 6997801, Tel Aviv-Yafo, Israel.
David GrosharTel Aviv University, 6997801, Tel Aviv-Yafo, Israel.
Bruse R RosenAthinoula A. Martinos Center for Biomedical Imaging, Harvard Medical School, 149 13th Street, Charlestown, MA, 02129, USA.
Onofrio Antonio CatalanoDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA, 02114, USA. onofriocatalano@yahoo.it.ORCID http://orcid.org/0000-0001-7733-4138
Harvard University · USTel Aviv University · ILBrigham and Women's Hospital · USEssen University Hospital · DESiemens Healthineers (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo compare standard (STD-DWI) single-shot echo-planar imaging DWI and simultaneous multislice (SMS) DWI during whole-body positron emission tomography (PET)/MRI regarding acquisition time, image quality, and lesion detection.

methodsEighty-three adults (47 females, 57%), median age of 64 years (IQR 52-71), were prospectively enrolled from August 2018 to March 2020. Inclusion criteria were (a) abdominal or pelvic tumors and (b) PET/MRI referral from a clinician. Patients were excluded if whole-body acquisition of STD-DWI and SMS-DWI sequences was not completed. The evaluated sequences were axial STD-DWI at b-values 50-400-800 s/mm

resultsThe median whole-body STD-DWI acquisition time was 14.8 min (IQR 14.1-16.0) versus 7.0 min (IQR 6.7-7.2) for whole-body SMS-DWI, p < 0.001. SMS-DWI image quality scores were higher than STD-DWI in the abdomen (OR 5.31, 95% CI 2.76-10.22, p < 0.001), but lower in the cervicothoracic junction (OR 0.21, 95% CI 0.10-0.43, p < 0.001). There was no significant difference in the chest, mediastinum, pelvis, and rectum. STD-DWI detected 276/352 (78%) lesions while SMS-DWI located 296/352 (84%, OR 1.46, 95% CI 1.02-2.07, p = 0.038).

conclusionsIn cancer staging and restaging, SMS-DWI abbreviates acquisition while maintaining or improving the diagnostic yield in most anatomic regions. KEY POINTS: • Simultaneous multislice diffusion-weighted imaging enables faster whole-body image acquisition. • Simultaneous multislice diffusion-weighted imaging maintains or improves image quality when compared to single-shot echo-planar diffusion-weighted imaging in most anatomical regions. • Simultaneous multislice diffusion-weighted imaging leads to superior lesion detection.

Indexed as

Diffusion Magnetic Resonance ImagingPositron-Emission TomographyWhole Body ImagingAgedEcho-Planar ImagingFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedReproducibility of ResultsDiffusion magnetic resonance imagingDWIEcho-planar imagingMultibandParallel imaging

Identifiers

PMID36460925
OpenAlexW4310642597

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.