Evidence map›Paper›PMID 36460839›Full record

ReviewInfectious diseases and therapy2023

Epidemiology of Varicella Zoster Virus and Herpes Zoster Virus in Gulf Cooperation Council Countries: A Review of the Literature.

Selim Badur, Onur Ozudogru, Mansour Khalaf, Serdar Ozturk, Sarah Albreiki, Salah Al Awaidy, Adriana Guzman-Holst

Open access · goldAbstract readReview
In one paragraph

Review in Infectious diseases and therapy, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Selim BadurGSK, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-0490-7203
Onur OzudogruGSK, Dubai, United Arab Emirates.ORCID http://orcid.org/0000-0002-7668-466X
Mansour KhalafGSK, Jeddah, Saudi Arabia.ORCID http://orcid.org/0000-0001-7899-5034
Serdar OzturkGSK, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-5885-6173
Sarah AlbreikiKing Fahd Hospital of the University, Dammam, Saudi Arabia.ORCID http://orcid.org/0000-0003-2109-8417
Salah Al AwaidyMinistry of Health, Muscat, Oman.ORCID http://orcid.org/0000-0001-5112-3893
Adriana Guzman-HolstGSK Vaccines, 20 Avenue Fleming, 1300, Wavre, Belgium. adriana.x.guzman@gsk.com.ORCID http://orcid.org/0000-0002-6753-2541
GlaxoSmithKline (Belgium) · BEKing Fahd Hospital of the University · SAMinistry of Health · OMUniversity of Jeddah · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe reactivation of varicella zoster virus (VZV) in previously infected individuals can cause herpes zoster (HZ), which is characterized by a localized, painful dermatomal rash. While there is a global trend of increasing HZ cases, there is a lack of research examining the epidemiology of HZ within the Gulf Cooperation Council (GCC) countries. Therefore, we aimed to critically appraise evidence on VZV and HZ epidemiology in the GCC countries and identify gaps in the current literature.

methodsA literature review was conducted via a comprehensive appraisal of the literature. PubMed and local-language journals were searched to identify articles related to HZ and VZV published up until 31 January 2022, with a sole focus on the GCC countries. Included studies reported on surveillance data, seroepidemiology, and patient outcomes for HZ and VZV, and comprised primary data reports, case series, case reports, narrative and systematic literature reviews, studies reporting HZ incidence or prevalence, and Ministry of Health reports.

resultsThirteen studies were found that reported on VZV seroprevalence in Saudi Arabia, the United Arab Emirates (UAE), and Qatar, ranging from 15.0% to 92.2%, while no data were identified for Bahrain, Kuwait, or Oman. There was very limited country-wide information on the incidence of HZ in GCC countries, and three identified studies reported HZ prevalence as seen in a single clinic, ranging from 0.62% to 2.3%. A single study from Saudi Arabia and government surveillance data reported on the impact of VZV vaccination on VZV infection, though there was no evidence on the impact of VZV vaccination on HZ.

conclusionThere is a clear gap in the literature regarding the incidence of HZ infection, and the impacts of HZ and VZV vaccinations in the GCC countries. Further research into the epidemiology of HZ is necessary to inform the implementation of vaccination programs in the GCC countries.

Indexed as

Chicken poxGCC countriesHerpes zosterShinglesVaricellaVaricella zoster virus

Identifiers

PMID36460839
PMCPMC9868198
OpenAlexW4310640237

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.