Evidence map›Paper›PMID 36460753›Full record

ArticleScientific reports2022

Long chain ceramides raise the main phase transition of monounsaturated phospholipids to physiological temperature.

Hiroshi Takahashi, Tomohiro Hayakawa, Asami Makino, Kunihiko Iwamoto, Kazuki Ito, Satoshi B Sato, Toshihide Kobayashi

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hiroshi TakahashiLipid Biology Laboratory, RIKEN, Wako, Saitama, 351-0198, Japan.
Tomohiro HayakawaLipid Biology Laboratory, RIKEN, Wako, Saitama, 351-0198, Japan.
Asami MakinoLipid Biology Laboratory, RIKEN, Wako, Saitama, 351-0198, Japan.
Kunihiko IwamotoLipid Biology Laboratory, RIKEN, Wako, Saitama, 351-0198, Japan.
Kazuki ItoRIKEN SPring-8 Center, Sayo, Hyogo, 679-5148, Japan.
Satoshi B SatoLipid Biology Laboratory, RIKEN, Wako, Saitama, 351-0198, Japan.
Toshihide KobayashiLipid Biology Laboratory, RIKEN, Wako, Saitama, 351-0198, Japan. toshihide.kobayashi@unistra.fr.
RIKEN · JPCentre National de la Recherche Scientifique · FRSPring-8 · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Little is known about the molecular mechanisms of ceramide-mediated cellular signaling. We examined the effects of palmitoyl ceramide (C16-ceramide) and stearoyl ceramide (C18-ceramide) on the phase behavior of 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine (POPE) using differential scanning calorimetry (DSC) and small- and wide-angle X-ray scattering (SAXS, WAXS). As previously published, the presence of ceramides increased the lamellar gel-to-lamellar liquid crystalline (L

Indexed as

CeramidesPhospholipidsEthanolaminesPhosphorylcholineScattering, Small AngleTemperatureX-Ray DiffractionCeramidesEthanolaminesN-palmitoylsphingosinePhospholipidsPhosphorylcholinephosphorylethanolamine

Identifiers

PMID36460753
PMCPMC9718810
OpenAlexW4311185418

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.