ArticleScientific reports2022
Antimicrobial activity of the methanolic leaf extract of Prosopis laevigata.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed.
- Phytochemical Diversity and Antimicrobial Potential of Fabaceae Species Occurring in Tamaulipas, Mexico: A Systematic Review.Plants (Basel, Switzerland) · 2026Review
- Antibacterial Activity and Chemical Analyses of the Alkaloidal Fraction ofMolecules (Basel, Switzerland) · 2025Article
- Antibacterial, Antifungal, and Wound-Healing Activities and Chemical Characterization of Propolis fromMolecules (Basel, Switzerland) · 2025Article
- Integrated Approach for the Optimization of the Sustainable Extraction of Polyphenols from a South American Abundant Edible Plant:Foods (Basel, Switzerland) · 2025Article
- Chemical Profile Analysis ofPlants (Basel, Switzerland) · 2025Article
- Growth, productivity and phytochemicals of Coriander in responses to foliar application of Acacia saligna fruit extract as a biostimulant under field conditions.Scientific reports · 2024Article
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Abstract
The appearance of antimicrobial-resistant pathogens has highlighted the need to search for new compounds that can effectively combat infectious diseases. A potential source of these compounds are the secondary metabolites of species that have been reported as effective traditional treatments of such diseases. Prosopis laevigata is a medicinal plant, and its chemical constituents have shown potential antimicrobial activity. In this study, the antimicrobial activities of the methanolic extract of the leaves of Prosopis laevigata against different bacterial and fungal strains of medical and agronomic interest were investigated in vitro. In addition, the chemical composition of this extract was investigated by HPLC-DAD, GC‒MS, and HPLC‒MS. The methanolic leaf extract contained 67 mg of GAE/g of total phenols (6.7%), 2.6 mg of QE/g of flavonoids (0.26%), and 11.87 mg of AE/g of total alkaloids (1.18%). Phenolic acids and catechol were the compounds identified by HPLC-DAD. The methanolic extract had strong antimicrobial activity, especially against Staphylococcus aureus (MIC = 0.62 mg/mL), Escherichia coli (MIC = 0.62 mg/mL), Candida tropicalis (MIC = 0.08 mg/mL) and Fusarium moniliforme (MIC = 4.62 mg/mL). These results suggest that the extract of P. laevigata leaves could be a source of antimicrobial molecules. However, it is necessary to delve into its chemical composition.
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