ArticleNature communications2022
Anterograde signaling controls plastid transcription via sigma factors separately from nuclear photosynthesis genes.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed, 33 citations in OpenAlex.
- Turning over a green leaf: integrating light signals toward chloroplast establishment.Plant physiology · 2026Review
- Vestigial Plastids in Parasitic Plants: Evolutionary Remnants or Adaptive Innovations?Plant, cell & environment · 2026Review
- Transcriptome Analysis Reveals Root EndophyteMicroorganisms · 2026Article
- Hexokinase 1 facilitates post-germinative seedling growth through its catalytic function.The Plant journal : for cell and molecular biology · 2026Article
- Conserved DNA architect couples chloroplast development to cell cycle in developing cotyledons.Nature plants · 2026Article
- Transient molecular chimerism for exploiting xenogeneic organelles.Nature communications · 2026Article
- Constant Illumination Boosts Rice Immunity via the Nicotinamide Mononucleotide Signaling Pathway: A Mechanistic Exploration.Rice (New York, N.Y.) · 2026Article
- A red/blue optoswitch for temporal control of chloroplast transcription and biogenesis in Arabidopsis.Nature communications · 2026Article
- Stromules: An Incident or Formalized Pathway for Molecules Transfer Between Organelles?International journal of molecular sciences · 2025Review
- The chloroplast-targeted long noncoding RNA CHLORELLA mediates chloroplast functional transition across leaf ageing via anterograde signalling.Nature plants · 2025Article
- Light-regulated dual-targeting of NUCLEAR CONTROL OF PEP ACTIVITY establishes photomorphogenesis via interorganellar communication.Plant physiology · 2025Article
- Metabolism in Sync: The Circadian Clock, a Central Hub for Light-Driven Chloroplastic and Mitochondrial Entrainment.Plants (Basel, Switzerland) · 2025Review
- De-etiolation is Almost Color Blind: The Study of Photosynthesis Awakening under Blue and Red Light.Plant & cell physiology · 2024Article
- HOT3/eIF5B1 confers Kozak motif-dependent translational control of photosynthesis-associated nuclear genes for chloroplast biogenesis.Nature communications · 2024Article
- Interference of skeleton photoperiod in circadian clock and photosynthetic efficiency of tea plant: in-depth analysis of mathematical model.Horticulture research · 2024Article
- What is going on inside of phytochrome B photobodies?The Plant cell · 2024Review
- Regulation of chloroplast biogenesis, development, and signaling by endogenous and exogenous cues.Physiology and molecular biology of plants : an international journal of functional plant biology · 2024Review
- Near-infrared light and PIF4 promote plant antiviral defense by enhancing RNA interference.Plant communications · 2024Article
- Chloroplast gene expression: Recent advances and perspectives.Plant communications · 2023Review
- Chimeric deletion mutation of rpoC2 underlies the leaf-patterning of Clivia miniata var. variegata.Plant cell reports · 2023Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 3 countries.
Funding
Abstract
Light initiates chloroplast biogenesis in Arabidopsis by eliminating PHYTOCHROME-INTERACTING transcription FACTORs (PIFs), which in turn de-represses nuclear photosynthesis genes, and synchronously, generates a nucleus-to-plastid (anterograde) signal that activates the plastid-encoded bacterial-type RNA polymerase (PEP) to transcribe plastid photosynthesis genes. However, the identity of the anterograde signal remains frustratingly elusive. The main challenge has been the difficulty to distinguish regulators from the plethora of necessary components for plastid transcription and other essential chloroplast functions, such as photosynthesis. Here, we show that the genome-wide induction of nuclear photosynthesis genes is insufficient to activate the PEP. PEP inhibition is imposed redundantly by multiple PIFs and requires PIF3's activator activity. Among the nuclear-encoded components of the PEP holoenzyme, we identify four light-inducible, PIF-repressed sigma factors as anterograde signals. Together, our results elucidate that light-dependent inhibition of PIFs activates plastid photosynthesis genes via sigma factors as anterograde signals in parallel with the induction of nuclear photosynthesis genes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.