ReviewESC heart failure2023
ACC/AHA/HFSA 2022 and ESC 2021 guidelines on heart failure comparison.
Review in ESC heart failure, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 8 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Comparison of loop diuretics for chronic heart failure: a systematic review and meta-analysis.European journal of clinical pharmacology · 2026Pooled it
- Heart failure in Somalia: a scoping review of the epidemiology, etiology, clinical characteristics, management, outcomes, and evidence gaps.Frontiers in cardiovascular medicine · 2026Pooled it
- Prognostic value of anion gap for patients with heart failure: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Prognostic value of albumin-based indices for mortality after heart failure: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Circulating brain-derived neurotrophic factor levels and heart failure: A systematic review and meta-analysis.ESC heart failure · 2024Pooled it
- Association between biomarkers of zinc and copper status and heart failure: a meta-analysis.ESC heart failure · 2024Pooled it
- The association between pulse wave velocity and heart failure: a systematic review and meta-analysis.Frontiers in cardiovascular medicine · 2024Pooled it
- Triglyceride-glucose index and heart failure: a systematic review and meta-analysis.Cardiovascular diabetology · 2023Pooled it
- Dronedarone provides effective early rhythm control: post-hoc analysis of the ATHENA trial using EAST-AFNET 4 criteria.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2025Trial
- Within a Heartbeat: A Machine Learning Approach Using VCG for Heart Failure Assessment in Sinus Rhythm.Journal of personalized medicine · 2026Article
- Heart Failure with Reduced and Mildly Reduced Ejection Fraction: A Network Interpretive Framework of Mechanisms, Phenotypes, and Therapeutic Response.International journal of molecular sciences · 2026Review
- Machine learning-based stratification of chagas heart failure severity using ECG power spectral biomarkers.Medical & biological engineering & computing · 2026Article
- Ceramides as Biomarkers and Pharmacological Targets in Heart Failure Pathophysiology.Biomolecules · 2026Review
- Psychosocial burden of cardiac patients: a retrospective in-patient analysis.BMC cardiovascular disorders · 2026Article
- Real-world safety profile of bisoprolol: signal detection and demographic stratification using the FAERS database.Naunyn-Schmiedeberg's archives of pharmacology · 2026Article
- An integrative approach to identify novel miRNA-mRNA interaction networks in LMNA-cardiomyopathy.Scientific reports · 2026Article
- Evaluation of Body Position Association with Diuretic Response and Neurohormonal Activation in Patients with Acutely Decompensated Heart Failure.Biomedicines · 2026Article
- Retrospective real-world study on effectiveness and safety of sacubitril/valsartan in Indian patients with heart failure.American journal of cardiovascular disease · 2026Article
- Empagliflozin Perception Mapping Survey.Cureus · 2025Article
- Nationwide Trends in Demographics, Comorbidities, and Mortality Among Elderly Patients with Heart Failure with Preserved Ejection Fraction Hospitalized with Cardiac Arrest.Journal of personalized medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The 2022 American College of Cardiology/American Heart Association/Heart Failure Society of America (ACC/AHA/HFSA) and the 2021 European Society of Cardiology (ESC) both provide evidence-based guides for the diagnosis and treatment of heart failure (HF). In this review, we aimed to compare recommendations suggested by these guidelines highlighting the differences and latest evidence mentioned in each of the guidelines. While the staging of HF depends on left ventricular ejection fraction, the Universal Definition of HF, suggested in 2021, is described in 2022 ACC/AHA/HFSA guidelines. Both guidelines recommend invasive and non-invasive tests to diagnose. Despite being identical in the backbone, some differences exist in medical therapy and devices, which can be partially attributed to the recent trials published that are presented in the American guidelines. The recommendation of implantable cardioverter defibrillator for prevention in HF with reduced ejection fraction (HFrEF) patients, made by ACC/AHA/HFSA guidelines, is among the bold differences. It seems that ACC/AHA/HFSA guidelines emphasize the quality of life, cost-effectiveness, and optimization of care given to patients. On the other hand, the ESC guidelines provide recommendations for certain comorbidities. This comparison can guide clinicians in choosing the proper approach for their own settings and the writing committees in addressing the differences in order to have better consistency in future guidelines.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.