Evidence map›Paper›PMID 36460472›Full record

ArticleNeurology2023

Interrater Reliability of Expert Electroencephalographers Identifying Seizures and Rhythmic and Periodic Patterns in EEGs.

Jin Jing, Wendong Ge, Aaron F Struck, Marta Bento Fernandes, Shenda Hong, Sungtae An, Safoora Fatima, Aline Herlopian, Ioannis Karakis, Jonathan J Halford and 37 more

Open access · greenAbstract read
In one paragraph

Article in Neurology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Unveiling variability: A systematic review of reproducibility in visual EEG analysis, with focus on seizures.Epileptic disorders : international epilepsy journal with videotape · 2024
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Navigating diagnostic overlap between seizures and movement disorders: A practical clinical approach.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Review
  7. Review
  8. Article
  9. Inter-Rater Reliability of EEG-Based Encephalopathy Grading.Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society · 2026
    Article
  10. Article
  11. Article
  12. ICU-EEG Pattern Detection by a Convolutional Neural Network.Annals of clinical and translational neurology · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Utility of the IFCN criteria for identifying interictal epileptiform discharges by experts: A decision hygiene approach to improve inter-rater reliability.Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

47 authors at 1 institution in 1 country.

Jin JingFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Wendong GeFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Aaron F StruckFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Marta Bento FernandesFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Shenda HongFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Sungtae AnFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Safoora FatimaFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Aline HerlopianFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Ioannis KarakisFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Jonathan J HalfordFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Marcus C NgFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Emily L JohnsonFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Brian L AppavuFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Rani A SarkisFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Gamaleldin OsmanFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Peter W KaplanFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Monica B DhakarFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Lakshman Arcot JayagopalFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Zubeda SheikhFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Olga TaraschenkoFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Sarah SchmittFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Hiba A HaiderFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Jennifer A KimFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Christa B SwisherFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Nicolas GaspardFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Mackenzie C CervenkaFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Andres A Rodriguez RuizFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Jong Woo LeeFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Mohammad TabaeizadehFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Emily J GilmoreFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Kristy NordstromFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Ji Yeoun YooFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Manisha G HolmesFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Susan T HermanFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Jennifer A WilliamsFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Jay PathmanathanFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Fábio A NascimentoFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Ziwei FanFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Samaneh NasiriFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Mouhsin M ShafiFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Sydney S CashFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Daniel B HochFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Andrew J ColeFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Eric S RosenthalFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Sahar F ZafarFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
Jimeng SunFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL.
M Brandon WestoverFrom the Massachusetts General Hospital/Harvard Medical School Department of Neurology (J.J., W.G., M.B.F., S.S.C., A.J.C., D.B.H., E.S.R., S.F.Z., M.B.W.), MA; Massachusetts General Hospital Clinical Data Animation Center (CDAC) (J.J., W.G., M.B.F., S.S.C., D.B.H., A.J.C., E.S.R., S.F.Z., M.B.W.), MA; University of Wisconsin-Madison Department of Neurology (A.F.S., S.F.); William S. Middleton Memorial Veterans Hospital Madison (A.F.S.), WI; National Institute of Health Data Science (S.H.), Peking University, Beijing, China; Georgia Institute of Technology (S.A.), College of Computing, Atlanta, GA; Yale University-Yale New Haven Hospital (A.H.), CT; Emory University School of Medicine (I.K.), GA; Medical University of South Carolina (J.J.H.), SC; University of Manitoba (M.C.N.), Canada; Johns Hopkins School of Medicine (E.L.J.), MD; University of Arizona College of Medicine (B.L.A.), AZ; Brigham and Women's Hospital (R.A.S.), MA; Mayo Clinic-Rochester (G.O.), MN; Warren Alpert School of Medicine of Brown University (M.B.D.), Providence, RI; University of Nebraska Medical Center (L.A.J.), NE; West Virginia University Hospitals (Z.S.), WV; University of Chicago (H.A.H.), Chicago, IL; Atrium Health (C.B.S.), NC; Université Libre de Bruxelles - Hôpital Erasme (N.G.), Belgium; Icahn School of Medicine, Mount Sinai (J.Y.Y.), NY; New York University (NYU) Grossman School of Medicine (M.G.H.), NY; Barrow Neurological Institute (S.T.H.), Phoenix, AZ; Mater Misericordiae University Hospital (J.A.W.), Dublin, Ireland; University of Pennsylvania (J.P.), PA; Beth Israel Deaconess Medical Center/Harvard Medical School (M.M.S.), MA; and University of Illinois at Urbana-Champaign (J.S.), College of Computing, Champaign, IL. mwestover@mgh.harvard.edu.
Massachusetts General Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Translational Imaging and Behavioral Assessment (TIBA) CoreP20GM130447 · NIGMS · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI CHRISTOPHER K KOVACH · 2020 to 2026
$20.7M
Data-Driven Sleep Biomarkers of Brain Health, Heart Health, and MortalityR01HL161253 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI CLIFFORD, GARI DAVID, MIGNOT, EMMANUEL J · 2022 to 2025
$8.3M
Neurophysiology of Human Cortical EpilepsyR01NS062092 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S · 2010 to 2021
$4.7M
Integrative Motor Activity Biomarker for the Risk of Alzheimer's RiskRF1AG064312 · NIA · BRIGHAM AND WOMEN'S HOSPITAL · PI HU, KUN · 2019 to 2019
$3.6M
Multimodal Network Connectivity Architecture (MOCA) of the Brain and its Role in the Recovery of Consciousness in Comatose Cardiac Arrest PatientsR01NS102574 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI GREER, DAVID MATTHEW, WU, ONA · 2018 to 2022
$3.4M
Investigation of Sleep in the Intensive Care Unit (ICU-SLEEP)R01NS102190 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI WESTOVER, MICHAEL BRANDON · 2018 to 2022
$3.2M
The Juvenile Myoclonic Epilepsy Connectome ProjectR01NS111022 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI STRUCK, AARON F · 2020 to 2024
$3.1M
Prospective Validation of Neurophysiologic Outcome Prediction in Acute Brain InjuryR01NS126282 · NINDS · BETH ISRAEL DEACONESS MEDICAL CENTER · PI Aaron F Struck, Michael Brandon Westover · 2023 to 2026
$2.9M
Big Data and Deep Learning for the Interictal-Ictal-Injury ContiuumR01NS107291 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI WESTOVER, MICHAEL BRANDON · 2018 to 2022
$2.8M
Establishing a Brain Health Index from the Sleep ElectroencephalogramRF1NS120947 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S, THOMAS, ROBERT JOSEPH · 2021 to 2021
$2.4M
Precision blood pressure management after endovascular stroke therapy based on real-time autoregulation measurementsK23NS110980 · NINDS · YALE UNIVERSITY · PI PETERSEN, NILS H. · 2020 to 2024
$951k
NCATS NIH HHS UL1 TR001863NHLBI NIH HHS R01 HL161253NIA NIH HHS R01 AG029289NIA NIH HHS RF1 AG064312NIGMS NIH HHS P20 GM130447NINDS NIH HHS F30 NS060325NINDS NIH HHS K23 NS110980NINDS NIH HHS K23 NS112596NINDS NIH HHS K24 NS088568NINDS NIH HHS R01 NS062092NINDS NIH HHS R01 NS102190NINDS NIH HHS R01 NS102574NINDS NIH HHS R01 NS107291NINDS NIH HHS R01 NS111022NINDS NIH HHS R01 NS126282NINDS NIH HHS R21 NS128641NINDS NIH HHS RF1 NS120947
6 · The paper itself

Abstract

BACKGROUND AND

objectivesThe validity of brain monitoring using electroencephalography (EEG), particularly to guide care in patients with acute or critical illness, requires that experts can reliably identify seizures and other potentially harmful rhythmic and periodic brain activity, collectively referred to as "ictal-interictal-injury continuum" (IIIC). Previous interrater reliability (IRR) studies are limited by small samples and selection bias. This study was conducted to assess the reliability of experts in identifying IIIC.

methodsThis prospective analysis included 30 experts with subspecialty clinical neurophysiology training from 18 institutions. Experts independently scored varying numbers of ten-second EEG segments as "seizure (SZ)," "lateralized periodic discharges (LPDs)," "generalized periodic discharges (GPDs)," "lateralized rhythmic delta activity (LRDA)," "generalized rhythmic delta activity (GRDA)," or "other." EEGs were performed for clinical indications at Massachusetts General Hospital between 2006 and 2020. Primary outcome measures were pairwise IRR (average percent agreement [PA] between pairs of experts) and majority IRR (average PA with group consensus) for each class and beyond chance agreement (κ). Secondary outcomes were calibration of expert scoring to group consensus, and latent trait analysis to investigate contributions of bias and noise to scoring variability.

resultsAmong 2,711 EEGs, 49% were from women, and the median (IQR) age was 55 (41) years. In total, experts scored 50,697 EEG segments; the median [range] number scored by each expert was 6,287.5 [1,002, 45,267]. Overall pairwise IRR was moderate (PA 52%, κ 42%), and majority IRR was substantial (PA 65%, κ 61%). Noise-bias analysis demonstrated that a single underlying receiver operating curve can account for most variation in experts' false-positive vs true-positive characteristics (median [range] of variance explained ([Formula: see text]): 95 [93, 98]%) and for most variation in experts' precision vs sensitivity characteristics ([Formula: see text]: 75 [59, 89]%). Thus, variation between experts is mostly attributable not to differences in expertise but rather to variation in decision thresholds. DISCUSSION: Our results provide precise estimates of expert reliability from a large and diverse sample and a parsimonious theory to explain the origin of disagreements between experts. The results also establish a standard for how well an automated IIIC classifier must perform to match experts. CLASSIFICATION OF EVIDENCE: This study provides Class II evidence that an independent expert review reliably identifies ictal-interictal injury continuum patterns on EEG compared with expert consensus.

Indexed as

ElectroencephalographySeizuresBrainCritical IllnessFemaleHumansMiddle AgedReproducibility of Results

Identifiers

PMID36460472
PMCPMC10136018
OpenAlexW4310643398

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.