Evidence map›Paper›PMID 36460341›Full record

ReviewJournal of nuclear medicine : official publication, Society of Nuclear Medicine2023

Imaging of Activated T Cells.

Mohammad O Sako, Benjamin M Larimer

Abstract readReview
In one paragraph

Review in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Monitoring T-Cell Activation in the Tumor Microenvironment by PET Imaging of the Chemokine CXCL9.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  3. Approaches to Imaging Immune Activation Using PET.Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Review
  4. Visualizing T-cell activation: PET imaging of CXCL9 as a window into the tumor immune response.American journal of nuclear medicine and molecular imaging · 2025
    Article
  5. Total-Body Dynamic Imaging and Kinetic Modeling of [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2024
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mohammad O SakoDepartment of Radiology, University of Alabama at Birmingham, Birmingham, Alabama.
Benjamin M LarimerDepartment of Radiology, University of Alabama at Birmingham, Birmingham, Alabama; blarimer@uab.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The adaptive immune response plays a critical role in detecting, eliminating, and creating a memory toward foreign pathogens and malignant cells. Demonstration of the specific and effective target killing of T cells in cancer has reignited interest in the study and therapeutic manipulation of the interaction between tumor and immune system. To both improve therapeutic efficacy and reduce adverse events, accurate monitoring of the activation of T cells is required. Several approaches to monitoring not just the presence, but importantly the activation, of T cells have been developed. Here, we review the recent advances in T-cell activation imaging and future directions for potential implementation into clinical utility.

Indexed as

NeoplasmsAdaptive ImmunityDiagnostic ImagingHumansImmunotherapyT-LymphocytescancerimmunotherapyPETT cells

Identifiers

PMID36460341
PMCPMC9841244

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.