Evidence map›Paper›PMID 36460339›Full record

ArticleThe Journal of pharmacology and experimental therapeutics2023

Protein 14-3-3 Influences the Response of the Cardiac Sodium Channel Na

Yang Zheng, Isabelle Deschênes

Open access · greenAbstract read
In one paragraph

Article in The Journal of pharmacology and experimental therapeutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Late IMedicinal research reviews · 2026
    Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yang ZhengDepartment of Physiology and Cell Biology, Frick Center for Heart Failure and Arrhythmias, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio (Y.Z., I.D.) and Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio (Y.Z.).
Isabelle DeschênesDepartment of Physiology and Cell Biology, Frick Center for Heart Failure and Arrhythmias, Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio (Y.Z., I.D.) and Department of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio (Y.Z.) isabelle.deschenes@osumc.edu.ORCID 0000-0002-1812-7267
The Ohio State University · US

Funding

Sodium Channels and Cardiac ArrhythmiasR01HL094450 · NHLBI · OHIO STATE UNIVERSITY · PI DESCHENES, ISABELLE · 2010 to 2022
$4.0M
Cardiac Ion Channel RegulationR01HL096962 · NHLBI · OHIO STATE UNIVERSITY · PI DESCHENES, ISABELLE, TSENG, GEA-NY · 2010 to 2021
$3.6M
NHLBI NIH HHS R01 HL094450NHLBI NIH HHS R01 HL096962
6 · The paper itself

Abstract

The cardiac sodium channel Na

Indexed as

Anti-Arrhythmia AgentsMexiletine14-3-3 ProteinsHEK293 CellsHumansLidocaineQuinidineSodium Channels14-3-3 ProteinsAnti-Arrhythmia AgentsLidocaineMexiletineQuinidineSodium Channels

Identifiers

PMID36460339
PMCPMC9976794
OpenAlexW4311131744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.