Evidence map›Paper›PMID 36460308›Full record

ArticleOpen heart2022

Patient-oriented risk score for predicting death 1 year after myocardial infarction: the SweDen risk score.

Rebecca Tremain Rylance, Philippe Wagner, Kevin K W Olesen, Jonas Carlson, Joakim Alfredsson, Tomas Jernberg, Margret Leosdottir, Pelle Johansson, Peter Vasko, Michael Maeng and 2 more

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Article in Open heart, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

12 authors.

Rebecca Tremain RylanceDepartment of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden rebecca.rylance@med.lu.se.ORCID 0000-0002-5921-3786
Philippe WagnerCenter for Clinical Research, Uppsala University, Uppsala, Sweden.
Kevin K W OlesenDepartment of Cardiology, Aarhus University Hospital, Aarhus, Denmark.
Jonas CarlsonDepartment of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.
Joakim AlfredssonDepartment of Cardiology, Karolinska University Hospital, Linkoping, Sweden.
Tomas JernbergThe Swedish Heart and Lung Association, Stockholm, Sweden.
Margret LeosdottirDepartment of Clinical Sciences, Skåne University Hospital Lund, Malmö, Sweden.ORCID 0000-0003-1677-1566
Pelle JohanssonThe Swedish Heart Failure Registry, Stockholm, Sweden.
Peter VaskoDepartment of Cardiology, Karolinska University Hospital, Linkoping, Sweden.
Michael MaengDepartment of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.
Moman Aladdin MohammedDepartment of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.
David ErlingeDepartment of Cardiology, Clinical Sciences, Lund University and Skåne University Hospital, Lund, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOur aim was to derive, based on the SWEDEHEART registry, and validate, using the Western Denmark Heart registry, a patient-oriented risk score, the SweDen score, which could calculate the risk of 1-year mortality following a myocardial infarction (MI).

methodsThe factors included in the SweDen score were age, sex, smoking, diabetes, heart failure and statin use. These were chosen a priori by the SWEDEHEART steering group based on the premise that the factors were information known by the patients themselves. The score was evaluated using various statistical methods such as time-dependent receiver operating characteristics curves of the linear predictor, area under the curve metrics, Kaplan-Meier survivor curves and the calibration slope.

resultsThe area under the curve values were 0.81 in the derivation data and 0.76 in the validation data. The Kaplan-Meier curves showed similar patient profiles across datasets. The calibration slope was 1.03 (95% CI 0.99 to 1.08) in the validation data using the linear predictor from the derivation data.

conclusionsThe SweDen risk score is a novel tool created for patient use. The risk score calculator will be available online and presents mortality risk on a colour scale to simplify interpretation and to avoid exact life span expectancies. It provides a validated patient-oriented risk score predicting the risk of death within 1 year after suffering an MI, which visualises the benefit of statin use and smoking cessation in a simple way.

Indexed as

Heart FailureHydroxymethylglutaryl-CoA Reductase InhibitorsMyocardial InfarctionHumansRisk FactorsSwedenHydroxymethylglutaryl-CoA Reductase Inhibitorsacute coronary syndromebiostatisticsmyocardial infarction

Identifiers

PMID36460308
PMCPMC9723953

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